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Physiological Environment Articles & Analysis

21 articles found

Comparative Analysis of X-ray Crystallography, NMR Spectroscopy, and Electron Microscopy for Structural Biology

Comparative Analysis of X-ray Crystallography, NMR Spectroscopy, and Electron Microscopy for Structural Biology

Advantages: l Solution-State Analysis: NMR allows structural determination in conditions mimicking physiological environments. l Dynamic Insights: Provides information on molecular flexibility, conformational changes, and interactions. ...

ByCreative Biostructure


3D Co-culture Models

3D Co-culture Models

Cell cultures have played a significant role in the academy and pharmaceutical industry, but conventional 2D cultures fail to provide physiological relevance and communication network as compared to in vivo conditions, since they are unable to mimic the complexity of cellular microenvironment, an essential part for the cell behavior and systematic investigation. ...

ByCreative Bioarray


Application of Nanoparticles in CRISPR/Cas9 Gene Therapy

Application of Nanoparticles in CRISPR/Cas9 Gene Therapy

LNPs-mediated mRNA Delivery Ionizable LNPs (iLNPs) in liposomes have been widely used in the study of mRNA delivery in recent years, mainly because they are neutral in physiological environments, but can ionize in the acidic environment of endosomes, causing overall collapse, solution to release the properties of the goods. ...

ByCD Bioparticles


How to Design a Good ADC Drug

How to Design a Good ADC Drug

Most ADCs are characterized by a cleavable linker, which releases cytotoxins through reduction, acidity, or proteolysis of the linker according to the physiological environment of the cell. On the other hand, for ADCs with non-cleavable linkers, the antibody would need to be degradedly completely after ADC internalization for the payload to be released. l Lysine ...

ByBOC Sciences


DNA-Stable Isotope Probing Technology (DNA-SIP)

DNA-Stable Isotope Probing Technology (DNA-SIP)

Background DNA-stable isotope probing technology (DNA-SIP) is a molecular ecology technology that uses stable isotopes to trace the genomic DNA of microorganisms in complex environments. Making use of stable isotopes to trace microbial genomic DNA in complicated environments can realize the transformation of research from single microbial ...

ByBOC Sciences


Do You Really Know Hydroxyapatite?

Do You Really Know Hydroxyapatite?

According to the chemical activity in the physiological environment, bioceramics can be divided into three types: Nearly inert bioceramics, only weak or no chemical reaction occurs when exposed to the physiological environment for a long time, and can maintain long-term stability; Surface-active bioceramics, can form chemical ...

ByMatexcel


Introduction to Microbiomics

Introduction to Microbiomics

The microbiome refers to the collection of all microorganisms and their genetic information in a specific environment or ecosystem, and its connotation includes the interaction of microorganisms with their environment and host. Microbiomics is the study of the microbiome, which explores their structure, function, and relationship with the ...

ByCreative Proteomics


Krill and Osmoregulation - Case Study

Krill and Osmoregulation - Case Study

The high salt content of the environment represents a strong physiological challenge for fish and crustacean. They need to keep their hemodinamic and a proper physiological status. This is particularly important in salmonids in captivity which are transported from fresh to sea water in a very short span. ...

ByKrill Canada Corporation


Introduction to Microbiomics

Introduction to Microbiomics

The microbiome refers to the collection of all microorganisms and their genetic information in a specific environment or ecosystem, and its connotation includes the interaction of microorganisms with their environment and host. Microbiomics is the study of the microbiome, which explores their structure, function, and relationship with the ...

ByCreative Proteomics


Local Raw Materials For Fish Feed In Nigeria

Local Raw Materials For Fish Feed In Nigeria

Furthermore, from the perspective of environment and economy, people should focus on using local feed ingredients to produce nutritional and healthy aquafeed through fish feed extruder and other equipment, reducing feed cost as well as creating an effective value chain and pull whole aquaculture industrial chain. ...

ByZhengzhou Fusmar Machinery Co., Ltd


Physiological and cellular responses of oysters (Crassostrea hongkongensis) in a multimetal‐contaminated estuary

Physiological and cellular responses of oysters (Crassostrea hongkongensis) in a multimetal‐contaminated estuary

In the present study, a euryhaline oyster, Crassostrea hongkongensis, was collected from different sites of the Pearl River estuary; and various physiological (heart rate, alkaline phosphatase as homeostatic regulation, and glycogen as energy reserve) and cytological (lysosomal membrane stability) biomarkers were quantified to assess this species as a potential bioindicator of ...

ByJohn Wiley & Sons, Ltd.


The influence of salinity on the fate and behavior of silver standardized nanomaterial and toxicity effects in the estuarine bivalve Scrobicularia plana

The influence of salinity on the fate and behavior of silver standardized nanomaterial and toxicity effects in the estuarine bivalve Scrobicularia plana

Finally, the present study highlighted salinity‐dependent changes in the physiology of estuarine bivalves. Environ Toxicol Chem 2016;9999:1–12. © 2016 SETAC ...

ByJohn Wiley & Sons, Ltd.


Evaluation of a portable MOS electronic nose to detect root rots in shade tree species

Evaluation of a portable MOS electronic nose to detect root rots in shade tree species

ABSTRACT The early detection of wood decays in high-value standing trees is very important in urban areas because mitigating control measures must be implemented long before tree failures result in property damage or injuries to citizens. Adverse urban environments increase physiological stresses in trees, causing greater susceptibility to attacks by pathogenic ...

ByPCA Technologies SRL


Synthesis of biphasic calcium phosphate powders by a simple hydrolysis process

Synthesis of biphasic calcium phosphate powders by a simple hydrolysis process

An ideal bone grafting material should be compatible with physiological environment, provoke osseous tissue formation and adapt degradation behaviour to new bone tissue growth. ...

ByInderscience Publishers


Variations in lethal and sublethal effects of cypermethrin among aquatic stages and species of anuran amphibians

Variations in lethal and sublethal effects of cypermethrin among aquatic stages and species of anuran amphibians

Unpredicted variation in levels of risk to organisms to xenobiotics can be observed, despite the use model species to predict the effects of chemicals in the environment. Physiological and morphological differences between species and life stages may lead to differences in sensitivity, while seasonal and spatial variation in pesticide concentrations may affect ...

ByJohn Wiley & Sons, Ltd.


The effects of salinity exposure on multiple life stages of a common freshwater mussel, Elliptio complanata

The effects of salinity exposure on multiple life stages of a common freshwater mussel, Elliptio complanata

Adult and larval Elliptio complanata were exposed to low level salt concentrations to determine the effects on mussel survival, physiology, and reproduction. Adults were exposed to salt concentrations of 0, 2, 4, and 6 ppt NaCl and monitored over 7 days for mortality. ...

ByJohn Wiley & Sons, Ltd.


Perfluorinated compound concentrations in great blue herons eggs near St. Paul, Minnesota, USA in 1993 and 2010–2011

Perfluorinated compound concentrations in great blue herons eggs near St. Paul, Minnesota, USA in 1993 and 2010–2011

These high concentrations are at levels associated with physiological and neurological effects in birds. Environ. Toxicol. Chem. © 2013 SETAC ...

ByJohn Wiley & Sons, Ltd.


In vitro exposure to fullerene C60 influences redox state and lipid peroxidation in brain and gills from Cyprinus carpio (Cyprinidae)

In vitro exposure to fullerene C60 influences redox state and lipid peroxidation in brain and gills from Cyprinus carpio (Cyprinidae)

Studies concerning the impact of nanomaterials, especially fullerene (C60), in fresh water environments and their effects on the physiology of aquatic organisms are still scarce and conflicting. ...

ByJohn Wiley & Sons, Ltd.


Differential binding of serum proteins to nanoparticles

Differential binding of serum proteins to nanoparticles

In the physiological environment, endogenous proteins readily adsorb to the surface of foreign materials. ...

ByInderscience Publishers


The thermal work limit is a simple reliable heat index for the protection of workers in thermally stressful environments

The thermal work limit is a simple reliable heat index for the protection of workers in thermally stressful environments

Objectives: To evaluate the Thermal Work Limit (TWL), in a controlled environment and under field conditions, against these criteria. Methods: Volunteers performed graded work in a controlled thermal environment to determine the limiting workload for the conditions. ...

ByScarlet Tech Ltd.

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