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Quantitative Risk Assessment Articles & Analysis

84 articles found

HCP Residual Detection: Ensuring Biopharmaceutical Safety and Quality

HCP Residual Detection: Ensuring Biopharmaceutical Safety and Quality

ELISAEnzyme-linked immunosorbent assay (ELISA) is the standard method for HCP detection because it provides quick, quantitative results. However, it relies on the availability and specificity of antibodies and may not detect all HCPs.2. ...

ByMtoZ Biolabs


Analysis of Host Cell Proteins (HCPs): Methods, Challenges, and an Efficient MWCO-Based Characterization Technique

Analysis of Host Cell Proteins (HCPs): Methods, Challenges, and an Efficient MWCO-Based Characterization Technique

The presence of host cell proteins (HCPs) in therapeutic protein drugs can have adverse effects on the production process and product performance. To effectively assess and control the risks associated with HCPs in therapeutic protein products, it is crucial to develop methods that can identify and monitor all HCP components. Traditional Methods and their ...

ByCreative Proteomics


IFRA Standards: What You Need to Know

IFRA Standards: What You Need to Know

If you are associated with the fragrance industry or are interested in fragrances, you have most likely heard of IFRA. The International Fragrance Association (IFRA) is the global body that represents the fragrance industry. IFRA plays a vital role in ensuring that the fragrances produced and used worldwide are safe for people and the environment. This blog will outline what you need to know ...

ByData Essence Limited


IFRA Standards: What You Need to Know

IFRA Standards: What You Need to Know

If you are associated with the fragrance industry or are interested in fragrances, you have most likely heard of IFRA. The International Fragrance Association (IFRA) is the global body that represents the fragrance industry. IFRA plays a vital role in ensuring that the fragrances produced and used worldwide are safe for people and the environment. This blog will outline what you need to know ...

ByData Essence Limited


Characterization, Remediation and Management in Kansas of Total Petroleum Hydrocarbons (TPH) and Light Non-Aqueous Phase Liquid (LNAPL)

Characterization, Remediation and Management in Kansas of Total Petroleum Hydrocarbons (TPH) and Light Non-Aqueous Phase Liquid (LNAPL)

The assessment of site conditions and the development of a conceptual site model (CSM) is crucial for the applications of this policy. ...

ByESdat Environmental Data Software


As the global health community tracks the spread of this virus, it’s important for water and wastewater professionals to keep updated on potential impacts

As the global health community tracks the spread of this virus, it’s important for water and wastewater professionals to keep updated on potential impacts

It's hard to miss the headlines. The recent outbreak of novel coronavirus disease (COVID-19) has dominated news cycles in recent months. But what information do we have that is related to coronaviruses in water and wastewater systems? And what can water- and wastewater-system operators do to protect public health? Modern water and wastewater treatment systems play an important role in public ...

ByBCR Environmental Corporation


Soil Generic Assessment Criteria for Human Health Risk Assessment

Soil Generic Assessment Criteria for Human Health Risk Assessment

Soil Generic Assessment Criteria for Human Health Risk Assessment is a technique used to examine the dangers which result from the release of pollutants into the land. ...

ByESdat Environmental Data Software


Understanding the IFRA 49th Amendment: What You Need to Know

Understanding the IFRA 49th Amendment: What You Need to Know

The fragrance industry is constantly evolving, with new regulations and standards being implemented to ensure consumer safety. One significant amendment that has captured the attention of fragrance professionals is the IFRA 49th Amendment. In this blog, we will delve into the details of this amendment and explore its key implications. Understanding the IFRA 49th Amendment is crucial for anyone ...

ByData Essence Limited


Scott J. Burya, Ph.D. Joins The Acta Group and Bergeson & Campbell, P.C.

Scott J. Burya, Ph.D. Joins The Acta Group and Bergeson & Campbell, P.C.

Burya holds a Ph.D. in analytical chemistry from the Ohio State University and will support clients in all stages of product development, from assessing the toxicology and regulatory profiles of new substances, performing quantitative risk assessments, and navigating state and federal regulations, to guiding teams through complex ...

ByBergeson & Campbell, P.C.


Quantitative microbial risk assessment to estimate the health risk from exposure to noroviruses in polluted surface water in South Africa

Quantitative microbial risk assessment to estimate the health risk from exposure to noroviruses in polluted surface water in South Africa

This study assessed the risks posed by noroviruses (NoVs) in surface water used for drinking, domestic, and recreational purposes in South Africa (SA), using a quantitative microbial risk assessment (QMRA) methodology that took a probabilistic approach coupling an exposure assessment with ...

ByIWA Publishing


Development of a Sanitation Safety Plan for improving the sanitation system in peri-urban areas of Iringa, Tanzania

Development of a Sanitation Safety Plan for improving the sanitation system in peri-urban areas of Iringa, Tanzania

The study presents the methodology and its adaptation and use for the given context, in order to assess risks and to support stakeholders in improving the current sanitation system and validate the design of an improved one. First results of the application of the methodology, obtained in one of the four peri-urban wards of Iringa, demonstrated its efficacy and ...

ByIWA Publishing


Ingestion of swimming pool water by recreational swimmers

Ingestion of swimming pool water by recreational swimmers

The volume of water ingested by swimmers while swimming is of great interest to individuals who develop risk assessments using quantitative microbial risk assessment or epidemiological approaches. ...

ByIWA Publishing


Water reuse through managed aquifer recharge (MAR): assessment of regulations/guidelines and case studies

Water reuse through managed aquifer recharge (MAR): assessment of regulations/guidelines and case studies

This paper recommends the development of specific regulatory or design criteria, including a complete quantitative risk assessment framework for the evaluation and operation of MAR systems. ...

ByIWA Publishing


EPA Issues FIFRA SAP Minutes on EPA Proposal to Use Biomonitoring Data to Derive a PoD for Chlorpyrifos

EPA Issues FIFRA SAP Minutes on EPA Proposal to Use Biomonitoring Data to Derive a PoD for Chlorpyrifos

The minutes indicate that the SAP has significant concerns with EPA’s proposal to use the biomonitoring chlorpyrifos data from the CCCEH epidemiology studies to establish a point of departure (PoD) for chlorpyrifos risk assessment. The minutes state: “Because many uncertainties cannot be clarified, the majority of the Panel does not have confidence ...

ByBergeson & Campbell, P.C.


Microbial risk in wastewater irrigated lettuce: comparing Escherichia coli contamination from an experimental site with a laboratory approach

Microbial risk in wastewater irrigated lettuce: comparing Escherichia coli contamination from an experimental site with a laboratory approach

This study assessed the contamination of Escherichia coli, in lettuce grown with treated domestic wastewater in four different irrigation configurations: open spray, spray under plastic sheet cover, open drip and drip under plastic sheet cover. ...

ByIWA Publishing


Does the use of tubular digesters to treat livestock waste lower the risk of infection from Cryptosporidium parvum and Giardia lamblia?

Does the use of tubular digesters to treat livestock waste lower the risk of infection from Cryptosporidium parvum and Giardia lamblia?

Worldwide, high incidences of cryptosporidiosis and giardiasis are attributed to livestock waste. Quantitative microbial risk assessment can be used to estimate the risk of livestock related infections from Cryptosporidium parvum and Giardia lamblia. The objective of this paper was to assess the occupational ...

ByIWA Publishing


QMRA and water safety management: review of application in drinking water systems

QMRA and water safety management: review of application in drinking water systems

Quantitative microbial risk assessment (QMRA), the assessment of microbial risks when model inputs and estimated health impacts are explicitly quantified, is a valuable tool to support water safety plans (WSP). ...

ByIWA Publishing


Ecotoxicity of halloysite nanotubes supported palladium nanoparticles on Raphanus sativus L.

Ecotoxicity of halloysite nanotubes supported palladium nanoparticles on Raphanus sativus L.

Up to date there are no studies on phytotoxic effects of functionalized halloysite (f‐HNTs). To develop a quantitative risk assessment model for predicting the potential impact of halloysite nanotubes supported palladium nanoparticles (HNT‐PdNPs) on plant life, we investigated their effect on seed germination, seedling development and mitotic ...

ByJohn Wiley & Sons, Ltd.


Scenario-based quantitative microbial risk assessment to evaluate the robustness of a drinking water treatment plant

Scenario-based quantitative microbial risk assessment to evaluate the robustness of a drinking water treatment plant

While traditional application of quantitative microbial risk assessment (QMRA) models usually stops at analyzing the microbial risk under typical operating conditions, this paper proposes the use of scenario-based risk assessment to predict the impact of potential challenges on the expected ...

ByIWA Publishing


Health impact assessment of wastewater reuse for replenishing an urban landscape lake by disability-adjusted life year

Health impact assessment of wastewater reuse for replenishing an urban landscape lake by disability-adjusted life year

The disease burden, expressed by disability-adjusted life year (DALY) was evaluated and compared with the infection risk obtained by quantitative microbial risk assessment. Findings showed that the disease burden due to road flushing was highest compared to the other pathways. For the different pathogens, E. coli was the leading ...

ByIWA Publishing

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