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Rna Oligonucleotide Articles & Analysis

9 articles found

What is the biotin labeled RNA?

What is the biotin labeled RNA?

Biotin-labeled RNA denotes RNA molecules that have undergone chemical modification via the inclusion of biotin, a water-soluble vitamin often known as vitamin B7 or H. ...

ByBOC Sciences


dsRNA Production: Techniques and Applications

dsRNA Production: Techniques and Applications

This technique utilizes bacteriophage RNA polymerases, such as T7, T3, or SP6, to synthesize RNA from a DNA template. By designing a DNA plasmid that contains the target gene sequences flanked by suitable promoter regions, researchers can transcribe the DNA into single-stranded RNA. Subsequently, two complementary RNA strands are ...

ByCreative Biogene


Frontiers in Antiviral Research 2024

Frontiers in Antiviral Research 2024

For example, companies are exploring the use of broad-spectrum antivirals that can inhibit multiple strains of viruses, providing a safeguard against emerging viral threats. RNA-Based Therapeutics RNA-based therapies, particularly those employing RNA interference (RNAi) and antisense oligonucleotides, are making significant ...

ByBOC Sciences


Targeting RNA Splicing: Mechanisms and Strategies   

Targeting RNA Splicing: Mechanisms and Strategies  

What Is RNA Splicing? RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. ...

ByCD Genomics


Hybridization-ELISA in the Bioassay of Oligonucleotide Drugs

Hybridization-ELISA in the Bioassay of Oligonucleotide Drugs

According to their therapeutic mechanisms, oligonucleotide drugs can be categorized into antisense oligonucleotides (ASOs), small interfering RNA (siRNA), microRNA, anti-gene transcription factor inducers, and nucleic acid aptamers. ...

ByBOC Sciences


RNA Splicing and How to Target It

RNA Splicing and How to Target It

What Is RNA Splicing? RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. ...

ByCD Genomics


Application of LC-MS in the Bioassay of Oligonucleotide Drugs

Application of LC-MS in the Bioassay of Oligonucleotide Drugs

Introduction of oligonucleotide drugs Oligonucleotides are a class of nucleic acid molecules consisting of dozens of nucleotides with short sequences. ...

ByBOC Sciences


Targeted Capture and Sequencing: An Accurate and Efficient Method for Human Pathogen Detection

Targeted Capture and Sequencing: An Accurate and Efficient Method for Human Pathogen Detection

Capture sequencing applies the use of transcript enrichment techniques wherein DNA or RNA probes are hybridized to the target region in the isolated DNA and then it is followed by high-throughput sequencing. It can be directly applied after nucleic acid isolation and library preparation. Short, single-stranded DNA or RNA oligonucleotide probes ...

ByCD Genomics


Why Choose Oligonucleotide Products and Services from BOC RNA?

Why Choose Oligonucleotide Products and Services from BOC RNA?

BOC RNA has accumulated important expertise in oligonucleotide analysis and purification. In terms of oligonucleotide analysis, BOC RNA has developed a hexafluoroisopropanol system to analyze oligonucleotides to get better results. For the purification of oligonucleotides, BOC ...

ByBOC Sciences

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