Stem Cell Line Articles & Analysis
7 articles found
This article explores the significance of drug screening in gene-edited cells, highlighting methodologies, benefits, and future directions. The Role of Gene-Edited Cells in Drug Screening Gene-edited cells enable precise modifications to the genome, allowing scientists to investigate the effects of specific genetic alterations on drug response. ...
CRISPR/Cas9 PlatformCB provides a point mutation cell line generation service for various cell lines, such as tumor cell lines and stem cell lines. ...
Under controlled and specific environments bioreactors are often used to cultivate a range of cell types (including mammalian cell lines and stem cells), microorganisms (such as fungi, yeasts and bacteria) and algae. Such cell cultures and microorganisms may be used for general research purposes ...
In a new study, researchers from the Icahn School of Medicine at Mount Sinai have developed a reproducible and scalable method to advance the maturation of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs), and hPSC-CMs produced by human stem cell lines in the laboratory support myocardial ...
In the study, the clinically approved anti-tumor drug doxorubicin was selected as the validation object, which confirmed that the "exosome nanoperforator" could efficiently load it into the exosome, and the drug-loaded exosome could transport doxorubicin into lung cancer cells and tumor spheres, induce cancer cell death and inhibit tumor sphere growth. ...
In the past, experts may have balked at the cost and difficulty of using primary human tissue: its limited viability; its need for multiple donors and the inconsistency this can bring; and its poor proliferative capacity. However, with new stem cell technologies, it is now possible to use primary human stem cells and induced ...
Publication Summary: Recent advances in the directed differentiation of human pluripotent stem cells to kidney organoids advances the prospect of drug screening, disease modelling, and even restoration of renal function using patient-derived stem cell lines. ...