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Uplc Ms Articles & Analysis

15 articles found

Can Herbal Medicine Protect Against Microplastic-Induced Lung Damage?

Can Herbal Medicine Protect Against Microplastic-Induced Lung Damage?

Polystyrene microplastics (PSMPs), small plastic fragments measuring less than 5 µm in diameter, are increasingly recognized as harmful air-borne pollutants. Studies demonstrate their ability to penetrate deep into the lungs, where they can induce oxidative stress, inflammation and airway remodeling. A recent study by Balkrishna et al. (2025) investigates these effects in a murine model and ...

BySCIREQ - an emka TECHNOLOGIES Company


Understanding Plant Hormones: Their Role, Extraction, and Detection   

Understanding Plant Hormones: Their Role, Extraction, and Detection  

Tandem mass spectrometry (MS/MS), which can be performed using time-tandem ion trap mass spectrometry or spatially tandem triple quadrupole (QQQ) mass spectrometry, is particularly effective for quantifying phytohormones. ...

ByCreative Proteomics


Hydrogen-Deuterium Exchange Mass Spectrometry Experiment

Hydrogen-Deuterium Exchange Mass Spectrometry Experiment

Therefore, studying the changes in the high-level structure of proteins in the drug design process is crucial for understanding the mode and function of potential drugs.Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS) is a mass spectrometry technique for studying the spatial conformation of proteins. ...

ByMtoZ Biolabs


Creative Proteomics Metabolomics Launches Coenzyme A (CoA) Analysis Service for Precision Metabolomics Research

Creative Proteomics Metabolomics Launches Coenzyme A (CoA) Analysis Service for Precision Metabolomics Research

Metabolomics, a division of Creative Proteomics, is dedicated to providing cutting-edge LC-MS-based metabolomics services for biomedical research institutions as well as biotechnological and pharmaceutical companies. ...

ByCreative Proteomics


Function and Detection of Bile Acids

Function and Detection of Bile Acids

Creative Proteomics provides animal target metabolomics services. UPLC-MS/MS technology combined with bile acid isotope standards allows simultaneous analysis of multiple bile acids and their adducts in biological matrices, enabling the analysis and quantification of bile acid species and significantly improving the accuracy of qualitative and ...

ByCreative Proteomics


Identification and risk assessment of human and veterinary antibiotics in the wastewater treatment plants and the adjacent sea in Tunisia

Identification and risk assessment of human and veterinary antibiotics in the wastewater treatment plants and the adjacent sea in Tunisia

In the following study, we came up with and validated a prompt, sensitive and precise method for the simultaneous determination of 56 antimicrobial drugs (tetracyclines, sulfonamides, β-lactams, macrolides and quinolones) using the ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). This method was implemented with ...

ByIWA Publishing


Photodegradation of the benzothiostrobin in solution and on soil and glass surface

Photodegradation of the benzothiostrobin in solution and on soil and glass surface

Three photodegradation products of benzothiostrobin were identified by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The photodegradation rates of benzothiostrobin increased with decreasing initial concentration of benzothiostrobin. ...

ByIWA Publishing


Advancing Omics Research and Reducing Bias with New MS Technology for Data-Independent Acquisition Experiments

Advancing Omics Research and Reducing Bias with New MS Technology for Data-Independent Acquisition Experiments

This means the results are not biased and no data is lost by the MS system switching between acquisition modes or experimental threshold limits, which is a concern for Data Dependent Acquisition (DDA) approaches. A new acquisition mode, 2D MS/MS, was first presented by Richardson, et al., at ASMS in 2015, and was recently introduced commercially ...

ByWaters Corporation


Chivas Brothers Limited - Case Study

Chivas Brothers Limited - Case Study

“We have four hydrogen generators for our GC-FID and GC-ECD analysis and two nitrogen generator to UPLC-MS/MS.” What prompted you to choose a Peak generator and how long have you used them? ...

ByPEAK Scientific Instruments Ltd


Oxidative transformation of oxcarbazepine by Cl2, ClO2 and O3: characteristics and pathways

Oxidative transformation of oxcarbazepine by Cl2, ClO2 and O3: characteristics and pathways

Reaction intermediates were evaluated by ultra performance liquid chromatography in combination with time-of-flight mass spectrometry (UPLC-Q-TOF-MS). Totals of 11, six and 10 intermediates were detected during the oxidation processes of chlorination, chlorine dioxide oxidation and ozonation, respectively. ...

ByIWA Publishing


Assessing the mutagenic effect potential of pharmaceuticals and of their transformation products. Implications in the gene expression profiling

Assessing the mutagenic effect potential of pharmaceuticals and of their transformation products. Implications in the gene expression profiling

Fourteen photo‐transformation products are proposed based on the m/z values resulting after a UPLC/MS/MS analysis. The transformation routes of the photolysed mixtures indicate a strong similarity with the ones obtained for each pharmaceutical separately. ...

ByJohn Wiley & Sons, Ltd.


What do an ancient Chinese Ruler and Waters’ Mass Spectrometry Research Team have in common?

What do an ancient Chinese Ruler and Waters’ Mass Spectrometry Research Team have in common?

If Waters Wilmslow ran out of tea it is likely the MS Research Team would struggle to function. The ancient Chinese Ruler, Emperor Jing Di, took tea to the grave with him for a cuppa in the afterlife. ...

ByWaters Corporation


Occurrence and removal efficiency of six polycyclic aromatic hydrocarbons in different wastewater treatment plants

Occurrence and removal efficiency of six polycyclic aromatic hydrocarbons in different wastewater treatment plants

Occurrence and removal efficiency of six polycyclic aromatic hydrocarbons (PAHs) (fluoranthene, benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, benzo[ghi]perylene and indeno[1,2,3-cd]pyrene) in wastewater were monitored at different treatment processes in three wastewater treatment plants (WWTPs) by using ultra performance liquid chromatography-tandem mass spectrometry ...

ByIWA Publishing


High performance liquid chromatography–tandem mass spectrometry for rapid and sensitive analysis of six polycyclic aromatic hydrocarbons in wastewater

High performance liquid chromatography–tandem mass spectrometry for rapid and sensitive analysis of six polycyclic aromatic hydrocarbons in wastewater

A sensitive and fast method was developed to quantitatively analyse the six polycyclic aromatic hydrocarbons (fluoranthene (FLT), benzo[b]fluoranthene (BbF), benzo[k]fluoranthene (BkF), benzo[a]pyrene (Bap), benzo[ghi]perylene (BghiP) and indeno[1,2,3-cd]pyrene (INPY)) by high performance liquid chromatography (UPLC) coupling with tandem mass spectrometry ...

ByIWA Publishing


Decolorization and degradation of reactive dye during the dyed cotton fabric rinsing process

Decolorization and degradation of reactive dye during the dyed cotton fabric rinsing process

The decolorization kinetics investigation showed that the decolorization of dyes during AO rinsing process followed the law of pseudo-first order kinetics. The result of UV-Vis and UPLC-MS analysis demonstrated that the dye was degraded into colorless organic molecular fragments and partly mineralized during the AO rinsing process.Keywords: active oxidation, COD, ...

ByIWA Publishing

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