Uplc System Articles & Analysis
10 articles found
Mass Spectrometry DetectionDeuterated peptides are separated by low-temperature HPLC/UPLC, and then entered into MS analysis. Based on the mass difference between hydrogen and deuterium, MS can monitor HDX changes by measuring the mass center displacement of peptides.5. ...
Liquid Chromatography Separation (LC) Use a liquid chromatography system (like UPLC) to separate the peptide segments to reduce the complexity of the mass spectrometry and increase the detection sensitivity. ...
In an ultra-high pressure liquid chromatography (UPLC) system that can withstand about 1×108 Pa, chromatographic columns with a pore size of 1.5 and 3 mm can be used, which is more suitable for rapid analysis of complex drug samples. ...
Estrogens are believed to have a negative effect on aquatic environments by disrupting the hormonal systems of fish; for example, they may contribute to intersex changes in fish. ...
Weller invested in an ACQUITY H-Class UPLC System and a SYNAPT G2-Si Mass Spectrometer with a grant from the U.S. ...
From a separations standpoint, we use several UPLC systems and we also have an SFC equivalent – the Waters ACQUITY UPC2. ...
Q3: Do you have to measure the system volume each time you start a new method? It is not necessary to re-measure the system volume unless some major component of the fluid path has been changed. ...
Here are my tips/best practices for column and HPLC/UHPC/UPLC system maintenance. Maintaining your LC columns Proper storage of HPLC columns will increase longevity and performance. ...
Yun Alelyunas and the research team at Waters have reported (pdf) on a microscale workflow that provides high-sensitivity quantitative results for small molecules and a peptide using a rapid, 3-minute gradient on the ionKey/MS microfluidics platform with an ACQUITY UPLC M-Class System and the Xevo G2-XS QTof Mass Spectrometer. This is comparable to the 2- to ...
Instruments include the ACQUITY UPLC I-Class System with a SYNAPT G2-Si High Definition Mass Spectrometer (HDMS) for chemical characterization and profiling, as well as an Alliance 2690 HPLC System with a single quadrupole detector for autopurification. ...