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Lung Capacity Articles & Analysis

27 news found

Validating The BLEO-Induced Mouse Model For Drug Discovery

Validating The BLEO-Induced Mouse Model For Drug Discovery

Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time. Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the ...

BySCIREQ - an emka TECHNOLOGIES Company


Advancing Tuberculosis Treatment: The Role of flexiVent In Evaluating Bacteriophage Therapy

Advancing Tuberculosis Treatment: The Role of flexiVent In Evaluating Bacteriophage Therapy

The rise of antibiotic-resistant bacteria has driven renewed interest in alternative treatments, including phage therapy. A recent study by Yang, F., et al (2024) explores the potential of bacteriophage therapy for treating multi-drug resistant Mycobacterium tuberculosis (Mtb) infections using humanized mouse models. This study highlights the efficacy of phage DS6A in reducing Mtb load ...

BySCIREQ - an emka TECHNOLOGIES Company


Studying Flow-Induced Pulmonary Hypertension and Compensatory Lung Growth: Insights from A Novel Murine Model

Studying Flow-Induced Pulmonary Hypertension and Compensatory Lung Growth: Insights from A Novel Murine Model

In the realm of pulmonary research, the search to understand complex lung conditions has led to the development of various animal models. Among these, a new murine model from Tsijis et al stands out for its potential to investigate flow-induced pulmonary hypertension (PH) and compensatory lung growth (CLG). This blog outlines this innovative model, its ...

BySCIREQ - an emka TECHNOLOGIES Company


Pulmonx Receives Japanese MHLW Approval of Zephyr Endobronchial Valve for the Treatment of Severe COPD/Emphysema

Pulmonx Receives Japanese MHLW Approval of Zephyr Endobronchial Valve for the Treatment of Severe COPD/Emphysema

The Zephyr Valve is a minimally invasive treatment option that can deliver significant benefits to patients including improvements in lung function, exercise capacity, and quality of life.1 Placed by bronchoscopy, with no cutting or incision, the valves are for patients who remain symptomatic despite optimal management including medications, pulmonary ...

ByPulmonx Corporation


Dr. Davies-Cutting Brings Industry Leading Technical Expertise to Nob Hill Therapeutics

Dr. Davies-Cutting Brings Industry Leading Technical Expertise to Nob Hill Therapeutics

Our differentiated device technology platform has the potential to simplify the delivery of higher efficiency inhalation drug products, making effective therapies available for patients with compromised lung function.” About Nob Hill Therapeutics: Nob Hill Therapeutics patented DryNeb™ Dry Powder Nebulizer is proven to deliver treatment drugs to the lower respiratory ...

ByNob Hill Therapeutics


Nob Hill Therapeutics Awarded HHS Phase II Grant and Announces New CEO

Nob Hill Therapeutics Awarded HHS Phase II Grant and Announces New CEO

The SBIR grant award further validates the potential benefit of this delivery technology to develop therapies to treat severe lung infections.” “This grant is built on our successful phase I grant work conducted a year ago, which delivered encouraging animal efficacy study results. ...

ByNob Hill Therapeutics


Dupixent (dupilumab) Approved by European Commission for Children Aged 6 to 11 Years with Severe Asthma with Type 2 Inflammation

Dupixent (dupilumab) Approved by European Commission for Children Aged 6 to 11 Years with Severe Asthma with Type 2 Inflammation

In addition to greatly reducing severe asthma attacks and improving lung function, patients in our clinical trials also reduced their oral corticosteroid use. ...

ByRegeneron Pharmaceuticals Inc.


FRI: In The transition from Research to Clinical Practice

FRI: In The transition from Research to Clinical Practice

It is not inconceivable that we will stop conducting lung function tests and perform a CT scan instead to determine lung capacity, residual volume, flow characteristics, and emphysema score. ...

ByFluidda


Dicerna Presents Data From Phase 1 Trial of Belcesiran at American Association for the Study of Liver Diseases (AASLD) The Liver Meeting® 2021

Dicerna Presents Data From Phase 1 Trial of Belcesiran at American Association for the Study of Liver Diseases (AASLD) The Liver Meeting® 2021

“We also look forward to expanding our inclusion criteria for ESTRELLA in the near-term to include patients on augmentation therapy – a key area of interest to us as patients with the liver manifestation can also present with AAT deficiency-associated lung disease.” The Phase 1 trial was designed to evaluate the safety, tolerability, pharmacokinetics and ...

ByNovo Nordisk A/S


FRI - Understanding The Link Between Pulmonary Vasculature Abnormalities and DCLO in Covid-19

FRI - Understanding The Link Between Pulmonary Vasculature Abnormalities and DCLO in Covid-19

CT images were evaluated by Functional Respiratory Imaging with automated tissue segmentation algorithms of the lungs and pulmonary vasculature. The diffusion capacity of carbon monoxide (DLCO) was obtained. ...

ByFluidda


Nob Hill Therapeutics Adds Seasoned Life Science Expert Paul Atkins as Executive Chairman

Nob Hill Therapeutics Adds Seasoned Life Science Expert Paul Atkins as Executive Chairman

Nob Hill Therapeutics aims to create effective inhalation therapies to address lower respiratory infections, the 5th leading overall cause of death worldwide, and other deadly lung diseases. Dr. Yun Li, Nob Hill Therapeutics CEO is excited to have Dr. ...

ByNob Hill Therapeutics


NDD’s new inline filters offer additional protection against COVID-19 during lung function tests

NDD’s new inline filters offer additional protection against COVID-19 during lung function tests

EasyOne spirometers are popular among pulmonologists and medical researchers as they are of the most sensitive devices available, delivering reliable, real-time lung function results and diagnosis of chronic lung diseases, even at the point of care. ...

ByNDD Medical Technologies


Washington sues feds over safety of nuclear waste tanks

Washington sues feds over safety of nuclear waste tanks

There were more than 50 reports of workers being exposed to vapors between January 2014 and April 2015, Ferguson said, and hundreds over the past few decades, with victims suffering from symptoms that include nosebleeds, brain damage and permanent loss of lung capacity. One longtime worker, Gary Sall, died from brain swelling linked to chemical vapors in 2011. ...

ByThe Associated Press


L.A. Story: Cleaner Air, Healthier Kids

"Improved air quality over the past 20 years has helped reduce the gap in lung health for kids inside, versus outside, the L.A. basin." The growing years are critical for lung development. ...

ByNational Institute of Environmental Health Sciences (NIEHS)


Wide gap between New Delhi, Beijing smog policies

Wide gap between New Delhi, Beijing smog policies

Air pollution is proven to exacerbate chronic lung ailments, and there is mounting evidence it also leads to stress, coronary diseases and inflammation. ...

ByThe Associated Press


Fuel delivery companies settle clean air violations at Idaho gas stations

Gasoline vapors lead to the formation of ground level ozone, an air pollutant that can trigger health problems including aggravated asthma, reduced lung capacity, and increased susceptibility to respiratory illnesses like pneumonia and bronchitis. ...

ByUS EPA - Environmental Protection Agency


Major operations begin on $25 million construction at Sunrise Landfill

These efforts are especially important because diesel exhaust is linked to reduced lung capacity and asthma, and is a likely human carcinogen. The EPA-approved remedy ensures effective control of the landfill with a durable and cost-effective landfill cover and stormwater system that address the unique geographic and climatic characteristics of Nevada’s ...

ByUS EPA - Environmental Protection Agency


EPA proposes criteria to waive federal requirements for capturing gasoline vapors when refueling vehicles/part of obama administration’s initiative to remove burdensome regulations

Ground-level ozone can cause acute respiratory problems, aggravated asthma, temporary decreases in lung capacity in healthy adults and inflammation of lung tissue. Children and the elderly are most at risk. ...

ByUS EPA - Environmental Protection Agency


Gasco to pay $350,000 penalty, install air emissions controls for violations at compressor facility on Uintah and Ouray Reservation

These pollutants can contribute to respiratory disorders such as asthma and reduced lung capacity, and many can adversely impact the heart, brain and nervous system. ...

ByUS EPA - Environmental Protection Agency


EPA to participate in USA science and engineering festival / encouraging the interest of our nation’s youth in science, technology, engineering and math (HQ)

Some examples of activities available at the EPA booth will include: Lung capacity challenge--learn how air quality impacts every breath we take; Drinking water filtration, demonstrating the engineering principles behind safe drinking water; Chemical reactions and discovering the potential issues of chemical mixtures; Exploring stormwater runoff and the ...

ByUS EPA - Environmental Protection Agency

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