Refine by
Brain Slice Equipment & Supplies
29 equipment items found
Manufactured by:Beacon Innovation International Inc (BIII) based inMarkham, ONTARIO (CANADA)
The Brain Slice Keeper AM has been designed with an integral heater and sensor element for preincubation of brain slices prior to transfer into recording chambers. In addition there is provision of inlet and outlet tubes to an external chamber incorporating multi-electrode ...
Manufactured by:Beacon Innovation International Inc (BIII) based inMarkham, ONTARIO (CANADA)
The BSC1 chamber design is similar to the original “Oslo chamber” (Langmoen & Andersen 1981) with later modifications (Dhanjal & Sears 1980, Alger et al 1984) to allow both interface and submerged methods of slice maintenance (Williams et al, 1993, Murphy et al, 1997, Bliss at al 2003). The temperature is controlled by a proportional control heating unit, the ...
Manufactured by:Beacon Innovation International Inc (BIII) based inMarkham, ONTARIO (CANADA)
The PTC03 is a proportional temperature control unit for use in conjunction with our brain slice chambers, perfusion solution heaters and an increasing range of other systems currently under development . A low voltage direct current output with low noise characteristics is used to power heating elements together with a sensor for feedback proportional ...
by:3Brain AG based inWadenswil, SWITZERLAND
The controlled environment allows label-free kinetic in vitro assays. The large sensing area of the per-well integrated microchip provides room for measuring either cell cultures, brain slices or brain organoids. Alpha is equipped with the latest generation of FPGA accelerators to manage real-time high-resolution data from up to 13824 (2304 per ...
Manufactured by:Rapp OptoElectronic based inWedel, GERMANY
The DF-Scope is equipped with dual detector paths, one positioned above and one below the sample, to maximize light collection. This configuration is especially beneficial for thin samples, such as brain slices, by utilizing sub-stage detectors for enhanced signal acquisition, adaptable with various Olympus ...
Manufactured by:SynVivo, Inc. based inHuntsville, ALABAMA (USA)
SynBBB blood-brain barrier model recreates the in vivo microenvironment by replicating a histological slice of brain tissue cells. The model is able to do this by communicating with endothelial cells across the blood-brain barrier (BBB). As a result, shear-induced endothelial cell tight junctions are easily achieved in the SynBBB ...
Manufactured by:World Precision Instruments, LLC (WPI) based inHitchin, UNITED KINGDOM
2-channel intracellular amplifier, For intracellular dual or differential studies, Built-in active filtering, Comes complete with 2 probe headstages, normally one high impedance and one low ...
Manufactured by:Campden Instruments (Vibrotome) based inLoughborough, UNITED KINGDOM
The 7000smz-2 Vibrotome by Campden Instruments is a highly precise vibrating microtome designed for creating tissue slices suitable for visual patch clamping and high-resolution imaging. Equipped with a z-axis calibration unit, this vibrotome minimizes blade adjustment errors, ensuring healthy, viable sections with minimal z-axis deflection. Operating at vibration speeds between ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
TACA (trans-4-Aminocrotonic acid) is a potent agonist of GABAA and GABAC receptors (KD= 0.6 μM). TACA also is GABA uptake inhibitor and substrate for GABA-T. TACA produces late biphasic responses in the MPG ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
(+)-Nipecotic acid ((+)-β-Homoproline) is a GABA transport inhibitor with potential antidepressant and anxiolytic activities. (+)-Nipecotic acid can increase the concentration of GABA in the synaptic cleft, thereby enhancing inhibitory neurotransmission. The research on (+)-Nipecotic acid provides a possible direction for the development of new inhibitory compounds for psychiatric ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 µM, 0.71 µM, 0.6 μM, and 0.98 µM, ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
PD 128907 is a D3 receptor ligand with activities of activating dopamine receptors, inhibiting cell firing, and inhibiting dopamine release. The active (+) enantiomer of PD 128907 has high affinity and selectivity for rat D3 dopamine receptors. PD 128907 inhibits cell firing in the ventral tegmental area and substantia nigra pars compacta with EC50 values of 33nM and 38nM, respectively. PD 128907 ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Lu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an EC50 of 500 nM for mGlu4 ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
PD81723 is an adenosine receptor binding enhancer. PD81723 enhances the inhibition of exogenous adenosine in a dose-dependent manner in hippocampal brain ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
DCG-IV is a potent agonist of group II mGluRs with EC50s of 0.35 and 0.09 μM for mGlu2R and mGlu3R, reapectively. DCG-IV is also a competitive antagonist at group I (IC50: mGlu1R/5R=389/630 μM) and III receptors (IC50: mGlu4R/6R/7R/8R= 22.5/39.6/40.1/32 μM). DCG-IV has anticonvulsive and neuroprotective ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent ...
Manufactured by:Campden Instruments (Vibrotome) based inLoughborough, UNITED KINGDOM
The Campden 9000SMZ Vibratome is a sophisticated vibrating microtome designed for precise sectioning of both live and fixed tissues. It is highly regarded in diverse research fields, including neuroscience, cardiac, lung, liver, organoid, and plant research. The device offers high precision in slicing, providing exceptional control over slice quality while maintaining tissue viability. Its ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Spadin, a natural peptide derived from a propeptide released in blood, is a potent TREK-1 channel blocker with IC50 value of 10 nM. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis. Spadin can be used for antidepressant ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
NAB-14 is a potent, selective, orally active and non-competitive GluN2C/2D antagonists with an IC50 of 580 nM for GluN1/GluN2D. NAB-14 shows >800-fold selective for recombinant GluN2C and GluN2D over GluN2A and GluN2B. NAB-14 can cross the ...