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Inflammatory Mediator Equipment & Supplies

133 equipment items found

Selleck Chemicals - Model A2853 - Gimsilumab (Anti-CSF2 / GM-CSF)

Selleck Chemicals - Model A2853 - Gimsilumab (Anti-CSF2 / GM-CSF)

Manufactured by:Selleck Chemicals LLC   based in, NORTH AMERICA
Gimsilumab (Anti-CSF2 / GM-CSF) is a human immunoglobulin G1 (IgG1) monoclonal antibody directed against the myeloid cell growth factor and inflammatory mediator granulocyte-macrophage colony-stimulating factor (GM-CSF) with potential immunomodulating activity. MW : 145.8 ...
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MedChemExpress - Model Ethyl linoleate - 544-35-4

MedChemExpress - Model Ethyl linoleate - 544-35-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory ...
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MedChemExpress - Model Lucyoside B - 91174-19-5

MedChemExpress - Model Lucyoside B - 91174-19-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Lucyoside B inhibits the production of inflammatory mediators via both NF-κB and activator protein-1 pathways in activated ...
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MedChemExpress - Model Ethyl linoleate (Standard) - 544-35-4

MedChemExpress - Model Ethyl linoleate (Standard) - 544-35-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ethyl linoleate (Linoleic Acid ethyl ester) inhibit the development of atherosclerotic lesions and the expression of inflammatory ...
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Boston - Model BOS-475 - Bromodomain and Extra Terminal (BET) Inhibitor

Boston - Model BOS-475 - Bromodomain and Extra Terminal (BET) Inhibitor

Manufactured by:Boston Pharmaceuticals   based inCambridge, MASSACHUSETTS (USA)
BOS-475 potently inhibits multiple clinically validated pathways (IL-12/IL-23-p40, Th17 cytokines and TNF) relevant to psoriasis pathophysiology. BOS-475 demonstrates broad inhibitory activities on other key disease-relevant immune-inflammatory mediators such as MCP-1, IL-6, and CXCL10 & 11. Topical BOS-475 is a potential treatment for psoriasis and other ...
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MedChemExpress - Model 2,5-Dihydroxyacetophenone - 490-78-8

MedChemExpress - Model 2,5-Dihydroxyacetophenone - 490-78-8

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
2,5-Dihydroxyacetophenone, isolated from Rehmannia glutinosa, inhibits the production of inflammatory mediators in activated macrophages by blocking the ERK1/2 and NF-κB signaling ...
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MedChemExpress - Model Turmeronol A - 131651-37-1

MedChemExpress - Model Turmeronol A - 131651-37-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Turmeronol A is a sesquiterpenoid compound.Turmeronol A has anti-inflammatory activity. Turmeronol A prevents macrophage activation and the production of inflammatory mediators by inhibiting the activation of NFκB. Turmeronol A can be used to prevent chronic inflammatory diseases ...
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MedChemExpress - Model Ethyl Caffeate - 102-37-4

MedChemExpress - Model Ethyl Caffeate - 102-37-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ethyl Caffeate is a natural phenolic compound isolated from Bidens pilosa. Ethyl caffeate suppresses NF-κB activation and its downstream inflammatory mediators, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), and prostaglandin E2 (PGE2) in vitro or in mouse ...
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MedChemExpress - Model Loratadine (Standard) - 79794-75-5

MedChemExpress - Model Loratadine (Standard) - 79794-75-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory ...
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Baxter Oxiris - Blood Purification Set

Baxter Oxiris - Blood Purification Set

Manufactured by:Baxter International Inc.   based inDeerfield, ILLINOIS (USA)
The Oxiris set is available in select countries around the world. Oxiris is the only blood purification filter set to effectively remove inflammatory mediators, endotoxin, fluid, and uremic toxins simultaneously. ...
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MedChemExpress - Model Loratadine - 79794-75-5

MedChemExpress - Model Loratadine - 79794-75-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory ...
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MedChemExpress - Model DBMB - 314027-66-2

MedChemExpress - Model DBMB - 314027-66-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
DBMB is an inhibitor of spleen tyrosine kinase (Syk), capable of significantly inhibiting the activity of Syk kinase. DBMB exhibits anti-inflammatory activity by suppressing the signaling of NF-κB, which in turn reduces the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2). DBMB can be utilized in research ...
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MedChemExpress - Model Rosiptor - 782487-28-9

MedChemExpress - Model Rosiptor - 782487-28-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Rosiptor (AQX-1125) is a selective and orally active phosphatase SHIP1 activator with anti-inflammatory effects. Rosiptor (AQX-1125) inhibits Akt phosphorylation, inflammatory mediator production and leukocyte chemotaxis in ...
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MedChemExpress - Model Hesperidin (Standard) - 520-26-3

MedChemExpress - Model Hesperidin (Standard) - 520-26-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic ...
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MedChemExpress - Model Olopatadine - 113806-05-6

MedChemExpress - Model Olopatadine - 113806-05-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic ...
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MedChemExpress - Model Alclometasone - 67452-97-5

MedChemExpress - Model Alclometasone - 67452-97-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Alclometasone (7a-Chloro-16a-methyl prednisolone) is a glucocorticoid and inhibits the release of pro-inflammatory mediators from leukocytes. Alclometasone can be used to relieve corticosteroid-responsive dermatoses, including atopic?dermatitis, eczema, psoriasis and allergic ...
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MedChemExpress - Model 2,4'-Dihydroxybenzophenone - 131-56-6

MedChemExpress - Model 2,4'-Dihydroxybenzophenone - 131-56-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
2,4′-Dihydroxybenzophenone (Ultraviolet absorber UV-0) occupies the hydrophobic pocket of MD2 and blocks the dimerization of TLR4. 2,4′-Dihydroxybenzophenone inhibits the LPS induced mtROS production, and LPS induced inflammatory response by downregulating pro-inflammatory mediators and decreasing the expression of MyD88, p-IRAK4, and NF-κB. ...
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MedChemExpress - Model Hesperidin - 520-26-3

MedChemExpress - Model Hesperidin - 520-26-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Hesperidin (Hesperetin 7-rutinoside), a flavanone glycoside, is isolated from citrus fruits. Hesperidin has numerous biological properties, such as decreasing inflammatory mediators and exerting significant antioxidant effects. Hesperidin also exhibits antitumor and antiallergic ...
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MedChemExpress - Model SB-657510 - 474960-44-6

MedChemExpress - Model SB-657510 - 474960-44-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
The Ki values are 61, 17, 30, 65 and 56 nM for human, monkey, cat, rat and mouse receptors, respectively. SB-657510 exerts anti-inflammatory effects by inhibiting UII-induced upregulation of inflammatory mediators such as adhesion molecules, cytokines, and tissue factor in human vascular endothelial ...
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MedChemExpress - Model 2,4'-Dihydroxybenzophenone (Standard) - 131-56-6

MedChemExpress - Model 2,4'-Dihydroxybenzophenone (Standard) - 131-56-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
This product is intended for research and analytical applications. 2,4′-Dihydroxybenzophenone (Ultraviolet absorber UV-0) occupies the hydrophobic pocket of MD2 and blocks the dimerization of TLR4. 2,4′-Dihydroxybenzophenone inhibits the LPS induced mtROS production, and LPS induced inflammatory response by downregulating pro-inflammatory ...
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