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Creative Bioarray Xprt Services Available In Seychelles
82 services found
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Glutaraldehyde stabilized red blood cells are produced from freshly washed turkey RBCs by brief exposure to a glutaraldehyde-buffer solution and exhaustive washing in ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Heat shock protein (HSP90) belongs to a family of molecular chaperones which are rapid and abundantly induced by stresses. HSP90 plays a crucial role in stabilizing denatured proteins that have become misfolded or unfolded because of cellular stress and by aiding in their re-folding. So far, many of the proteins identified as HSP90 clients are key components of the oncogenic phenotype involved in ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
As compounds move from discovery to development, the need for even more detailed and precise metabolite data becomes increasingly important, both to understand the characteristics of the candidate drug in humans and to fulfill the regulatory requirements that will underpin a successful drug registration. Creative Bioarray has deep expertise in the profiling, identification and structural ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Exosomes are cell-derived nanovesicles that can carry nucleic acids, proteins, lipids, and other molecules from the cells of their origin. Exosomes isolation are found in almost all biological fluids, including blood, saliva, urine, semen, sputum, breast milk, and cerebrospinal fluid. Unlike tissue samples, they can be collected non-invasively over a long period of time, allowing continuous ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
In vitro toxicology and in vitro toxicity testing involves the study and interpretation of adverse effects through in vitro research methods typically associated with bacterial and mammalian cell cultures. Creative Bioarray's in vitro toxicity testing uses the latest advances in the field of in vitro toxicology to help clients determine the viability of compounds early in the preclinical phase ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Single-Particle cryo-EM is an electron microscopy method used to determine structures of individual proteins and other macromolecular complexes. Structures of macromolecules can be determined from cryo-EM images at near-atomic and sometimes true atomic resolution. Single-Particle cryo-EM can be used to answer specific questions concerning protein-protein interactions and identify protein/domain ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
The CD34+/CD38- immunophenotype defines a primitive subpopulation of progenitor cells. Human Cord Blood CD34+/CD38- Progenitor Cells from Creative Bioarray are characterized by flow cytometry, analyzing cell viability and the presence of the CD34 and CD38 markers. Our cells have a purity of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
With a few exceptions, the immune system of humans and experimental animals are very similar. Most drugs that inhibit the immune system in humans produce similar results in rodents, and the mechanisms for immunosuppressive action are similar. Creative Bioarray has validated and implemented a series of standardized immunotoxicity testing protocols based on experimental animal models, which are ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Laser capture microdissection (LCM) is an automated sample preparation technique that allows the identification of specific substructures or cell types and their precise removal from the original tissue without causing damage. LCM has important advantages over other techniques for cell purification, especially in terms of precision, speed, simplicity and archiving capabilities. This technique of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Advances had been made towards the use of in vitro human skin equivalents/models for dermal drug and cosmetic product testing. In vitro Skin Models (Human Skin Equivalent, FTSK, HSE) used under defined test conditions offer several advantages: i) since most models are composed of primary human cells, inter-species extrapolation is avoided; ii) in contrast to human skin specimens, repeated ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Keratinocyte Cells are the most common skin cells, 90% of them are located on the out layer of the skin. The Keratinocyte Cells work as a barrier that protect the under skin layer tissue and nerves. This barrier can be found everywhere in our body, such as skin, hair, and nails, they are all made by keratin protein which produced by Keratinocyte Cells. Creative bioarray provides multiple types of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Kupffer cells are resident liver macrophages and play a critical role in maintaining liver function. Under physiological conditions, they are the first innate immune cells that protect the liver from bacterial infection. Under pathological conditions, they are activated by different components and can differentiate into M1-like (classical) or M2-like (alternative) macrophages. The metabolism of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Diabetic Type I and Type II Human Skeletal Muscle Myoblasts (HSMM) are isolated from donors diagnosed with either Diabetes Type I or Diabetes Type II. Additional donor information is available by contacting Scientific Support. Diseased cells are tested in the same SkGM™-2 Skeletal Muscle Growth Media as the normal cells allowing for easy comparisons between diseased and normal tissue. Both are ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cells are a population of cells from a multicellular organism due to mutation, which can escape normal cellular senescence and keep undergoing division. Thus, this kind of cells can grow in vitro for prolonged periods. The mutations required for immortality can occur naturally or be intentionally induced for experimental purposes. Immortal cell lines are a powerful tool for the ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray is committed to providing microsomal stability assay service with high effectivity and reliability to accelerate drug development. We provide microsomal stability assays for all small compounds such as pharmaceuticals, industrial chemicals, and clients' products. Creative Bioarray's microsomal stability assay can be further extended to metabolite profiling and give out more ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Primary human Corneal epithelial cells were isolated and transfected with full-length human telomerase reverse transcriptase (hTERT) expressing lentiviral particles. This immortalized human Corneal epithelial cells can that allows the establishment of a standardized, reproducible cornea barrier model. ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Microglia, one of the glial cell types in the CNS, is an important integral component of neuro-glial cell network. They have been observed in the brain parenchyma from the early stage of development to the mature state. Human Microglia (HM) act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured or pathologically damaged. Microglia can be ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Human iPSC-derived Microglia provide a reproducible, physiologically-relevant model in an easy-to-use, assay-ready format for investigating neuroglia involvement in neurodegeneration and neurodevelopment. We also offer a fully optimized serum-free Microglia Maintenance Medium to promote and support the maintenance of microglia. The method for generating iPSC-derived microglia mimics the in vivo ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
The carcinogenicity studies of rodents are intended to determine the potential risk of a test article on the development of cancer during long-term exposure. In addition, compounds that have a mutagenic potential or a structural alert indicating a putative carcinogenic effect or influence on cell proliferation also must be tested, even if these compounds only intended for short administration ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
In vivo studies are done toward the end of the lead optimization process on selected candidates for final characterization and selection. GLP studies are done only for development compounds being prepared for clinical trials. Creative Bioarray has conducted in vivo testing for cardiovascular disease using in vivo models for both side-effect profiling and efficacy according to your requirement. ...