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Creative Bioarray Xprt Services Available In Spain
82 services found
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Glutaraldehyde stabilized red blood cells are produced from freshly washed turkey RBCs by brief exposure to a glutaraldehyde-buffer solution and exhaustive washing in ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Heat shock protein (HSP90) belongs to a family of molecular chaperones which are rapid and abundantly induced by stresses. HSP90 plays a crucial role in stabilizing denatured proteins that have become misfolded or unfolded because of cellular stress and by aiding in their re-folding. So far, many of the proteins identified as HSP90 clients are key components of the oncogenic phenotype involved in ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
As compounds move from discovery to development, the need for even more detailed and precise metabolite data becomes increasingly important, both to understand the characteristics of the candidate drug in humans and to fulfill the regulatory requirements that will underpin a successful drug registration. Creative Bioarray has deep expertise in the profiling, identification and structural ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray has developed human highly immortalized differentiated cell lines from various human tissues that show stable growth characteristics and phenotypes and have a high potential for production of complex biopharmaceuticals such as recombinant proteins, vaccines or extracellular vesicles. Creative Bioarray provides already established cell lines to get proof-of-principle for new ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Exosomes are cell-derived nanovesicles that can carry nucleic acids, proteins, lipids, and other molecules from the cells of their origin. Exosomes isolation are found in almost all biological fluids, including blood, saliva, urine, semen, sputum, breast milk, and cerebrospinal fluid. Unlike tissue samples, they can be collected non-invasively over a long period of time, allowing continuous ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
In vitro toxicology and in vitro toxicity testing involves the study and interpretation of adverse effects through in vitro research methods typically associated with bacterial and mammalian cell cultures. Creative Bioarray's in vitro toxicity testing uses the latest advances in the field of in vitro toxicology to help clients determine the viability of compounds early in the preclinical phase ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
EBs are three-dimensional aggregation of three germ layer cells. The formation of Embryoid Body is a routine method for the differentiation of hiPSCs into different cell lineages. One of the major advantages of this method is that it is performed in vitro with standard tissue culture approaches and materials, thereby avoiding the regulatory problems and substantial costs associated with ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Migration is a key property of live cells and critical for normal development, immune response, and disease processes such as cancer metastasis and inflammation. Methods to examine cell migration are very useful and important for a wide range of biomedical research such as cancer biology, immunology, vascular biology, cell biology and developmental biology. With comprehensive list of cell lines ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Single-Particle cryo-EM is an electron microscopy method used to determine structures of individual proteins and other macromolecular complexes. Structures of macromolecules can be determined from cryo-EM images at near-atomic and sometimes true atomic resolution. Single-Particle cryo-EM can be used to answer specific questions concerning protein-protein interactions and identify protein/domain ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
The CD34+/CD38- immunophenotype defines a primitive subpopulation of progenitor cells. Human Cord Blood CD34+/CD38- Progenitor Cells from Creative Bioarray are characterized by flow cytometry, analyzing cell viability and the presence of the CD34 and CD38 markers. Our cells have a purity of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cell lines and services are of ever-increasing importance in various aspects of biomedicine, toxicology and biotechnology. The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. Besides, the immortalized cells have implications for the ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Immortalized cell lines and services are of ever-increasing importance in various aspects of biomedicine, toxicology and biotechnology. The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. Besides, the immortalized cells have implications for the ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
As sentinels of the immune system, Normal Human Dendritic Cells (DCs) are located in all tissues, especially those at the interface between the external environment and the body, such as lung, intestine, and skin. DCs are divided into plasmacytoid DCs (pDCs) and conventional DCs (cDCs), cDCs are further split into type 1 (cDC1) and type 2 (cDC2). Functionally, cDCs include two states: immature ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
With a few exceptions, the immune system of humans and experimental animals are very similar. Most drugs that inhibit the immune system in humans produce similar results in rodents, and the mechanisms for immunosuppressive action are similar. Creative Bioarray has validated and implemented a series of standardized immunotoxicity testing protocols based on experimental animal models, which are ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Laser capture microdissection (LCM) is an automated sample preparation technique that allows the identification of specific substructures or cell types and their precise removal from the original tissue without causing damage. LCM has important advantages over other techniques for cell purification, especially in terms of precision, speed, simplicity and archiving capabilities. This technique of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Human CD34+ Progenitor Cells, a transmembrane glycoprotein expressed on the surface of hematopoietic progenitor cells and small vascular endothelial cells, is considered to be a marker of hematopoietic stem cells and hematopoietic progenitor cells. CD34+ cells have been shown to possess colony-forming potential in short-term assays, maintain long-term colony-forming potential in in vitro culture, ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Advances had been made towards the use of in vitro human skin equivalents/models for dermal drug and cosmetic product testing. In vitro Skin Models (Human Skin Equivalent, FTSK, HSE) used under defined test conditions offer several advantages: i) since most models are composed of primary human cells, inter-species extrapolation is avoided; ii) in contrast to human skin specimens, repeated ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Primary human Corneal epithelial cells were isolated and transfected with full-length human telomerase reverse transcriptase (hTERT) expressing lentiviral particles. This immortalized human Corneal epithelial cells can that allows the establishment of a standardized, reproducible cornea barrier model. ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Microglia, one of the glial cell types in the CNS, is an important integral component of neuro-glial cell network. They have been observed in the brain parenchyma from the early stage of development to the mature state. Human Microglia (HM) act as brain macrophages when programmed cell death occurs during brain development or when the CNS is injured or pathologically damaged. Microglia can be ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Human iPSC-derived Microglia provide a reproducible, physiologically-relevant model in an easy-to-use, assay-ready format for investigating neuroglia involvement in neurodegeneration and neurodevelopment. We also offer a fully optimized serum-free Microglia Maintenance Medium to promote and support the maintenance of microglia. The method for generating iPSC-derived microglia mimics the in vivo ...