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Cryo Electron Microscope Services
14 services found
by:Health Technology Innovations, Inc. based inPortland, OREGON (USA)
HTI’s cryo-EM process for single particle analysis is iterative and deeply integrated with customer consultation to produce optimal 3-D atomic ...
by:Health Technology Innovations, Inc. based inPortland, OREGON (USA)
HTI employs cryo-EM services expertise collaborating with Pharma/Biotech science expertise to enable high-resolution structure determination of drug discovery targets. Here are a few of our leading customer ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Single-Particle cryo-EM is an electron microscopy method used to determine structures of individual proteins and other macromolecular complexes. Structures of macromolecules can be determined from cryo-EM images at near-atomic and sometimes true atomic resolution. Single-Particle cryo-EM can be used to answer specific questions concerning protein-protein interactions and identify protein/domain ...
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
Our partner service centers that include contract research organizations (CRO) offer three unique levels of cryo-EM service ideal for scientists who are curious about cryo-EM but want proof that the technology can provide high-value structural insights for their drug discovery projects. In this controlled environment, you can discover the value and true potential of cryo-EM for structure-based ...
by:Health Technology Innovations, Inc. based inPortland, OREGON (USA)
HTI employs cryo-EM services with your science expertise to enable high-resolution structure determination of your targets. Partnering with a network of image acquisition sites, we deploy our cryo-EM scientists to meet your unique requirements in a fast, affordable and scalable ...
by:Health Technology Innovations, Inc. based inPortland, OREGON (USA)
Cryo-EM is a powerful technology for determining high-resolution 3D structures of biological macromolecules and bound compounds. It is complementary to X-ray crystallography, NMR, and other biophysical ...
Manufactured by:CD Bioparticles based inShirley, NEW YORK (USA)
In the development of liposome related drug carriers, the characterization of lamellarity is of the same essential importance as size analysis. CD Bioparticles offers custom services to measure the lamellarity of liposomes in different sizes using advanced microscopic ...
Manufactured by:Proteros Biostructures GmbH based inMartinsried, GERMANY
We've already industrialized protein crystallography, now we're industrializing cryo-EM. We strive to deliver elucidation of even the most complex structures through the establishment of the RIGHT protein and application of premium cryo-EM platform technology and expertise. Cryo-EM is emerging as a method for determining structures of novel targets, where X-ray crystallography may not be ...
Manufactured by:Proteros Biostructures GmbH based inMartinsried, GERMANY
"One-Stop-Shop" for Expression, Analytics-Driven Purification, Characterization, Developability Assessment. Have you run your biologics discovery program, passed the engineering phase and are now at a stage where you would like to further characterize your biologics? At Proteros we are familiar with a wide variety of biologics formats (bs-Ab, ms-Abs, cytokines, non-human antibody formats and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The Cryo-EM Single Particle Analysis technique involves preparing numerous molecular samples with identical structures. These are dispersed and vitrified for random projection imaging, followed by computational angle determination and the alignment of particles with matching angles to emphasize distinctive, interpretable features. Assuming uniformity in molecular structure, the technique involves ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Microcrystal electron diffraction (MicroED) is a novel technique that uses cryo-transmission electron microscopy (Cryo-TEM) for the three-dimensional (3D) reconstruction of organic small molecules and biological macromolecule crystals based on electron diffraction data. As an emerging technology, MicroED employs electrons as the incident beam to acquire MicroED microcrystal electron diffraction ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cryo-electron tomography (cryo-ET) is an imaging technique used for high-resolution three-dimensional (3D) reconstructions of biomolecules, primarily for studying cellular structures. In cryo-ET, vitrified samples are imaged in a transmission electron microscope at tilts ranging from ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Structural biology is a field grounded in molecular biology, biochemistry, and biophysics, focusing on the detailed study of biomacromolecules such as proteins and nucleic acids. Its goal is to elucidate the fine structural details of biomacromolecules to understand the mechanisms behind their functional roles, thereby enhancing our understanding of life's processes. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Structural biology has always played a vital role in drug discovery because it provides the most direct and visible atomic-level information on drug targets and can be applied to every step of preclinical drug development, including target identification and design as well as lead compound optimization. Based on atomic resolution information about the active or regulatory sites of target ...