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Cytokine Services
63 services found
Manufactured by:Alkermes based inDublin 4, IRELAND
We are harnessing our established protein engineering platforms to develop novel cytokines with the potential to fight ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Obesity is a systemic disease, not only does it lead to changes in body shape, but it also brings along various diseases and complications, affecting an individual's overall health. Common complications, such as hyperglycemia, hyperlipidemia, and hypertension, are medically termed as "metabolic syndrome". The fluid factors secreted by adipose tissue propel the development of metabolic syndrome ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cell death occurs through several pathways including apoptosis, necrosis, and other emergent pathways. Apoptosis is pivotal in immune responses, involving processes such as intracellular balance, T cell clustering, the death of reactive lymphocytes, and cytotoxity of target cells. Apoptosis involves key components like APO-1/Fas, a receptor essential for apoptotic signaling; Caspase-3, crucial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
These disorders stem from abnormalities in three key areas: bone resorption, bone growth, and mineral deposition. Increasingly, research has identified numerous cytokines involved in the processes of bone remodeling and metabolism. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
During the tumor formation process, cancer cells release various cytokines and growth factors into the surroundings and reprogram many other types of cells to establish a tumor microenvironment. As a result, tumor tissues almost always contain a large number of endothelial cells, fibroblasts, and infiltrating inflammatory cells, which in turn produce various ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Several studies have shown that CpG ODN is able to stimulate cells that express TLR9, initiating an immunomodulatory cascade that culminates in the production of Th1 and proinflammatory cytokines and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Systemic lupus erythematosus (SLE) is a classic systemic autoimmune disorder characterized by impaired autoimmune tolerance and high concentration of autoantibodies targeting self-antigens, which lead to organ damage. This pathological process involves multiple cytokines. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Atopic Dermatitis (AD) is prevalent among children aged 1 to 5 years and a considerable number of patients carry this condition into adulthood. As a chronic inflammatory skin disease, AD often coexists with asthma and rhinitis. At the cellular level, the hallmark of AD is characterized by high serum IgE levels, where T cells play a crucial regulatory role. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cardiovascular diseases are usually associated with systemic inflammatory responses, such as increased expression of inflammatory proteins CRP, IL-1, IL-6, IL-18, and TNF-α. These proteins can be considered as diagnostic markers for the risk assessment of various cardiovascular diseases. For instance, CD40, which belongs to the tumor necrosis factor receptor superfamily, and CD40L play a crucial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Diabetes is marked by hyperglycemia, resulting from defects in insulin secretion and action, which disturbs the metabolism of carbohydrates, fats, and proteins. Type 1 Diabetes (T1D) is an autoimmune disease where T cells mediate inflammation and specifically damage pancreatic β ...
Manufactured by:Universal Biosensors based inRowville, AUSTRALIA
We pride ourselves on partnering with academic centres and researchers in the advance of science in hemostasis and thrombosis and we look to further these partnering opportunities in cytokine-based research in support of clinical trials. ...
by:Base Pair Biotechnologies, Inc. based inPearland, TEXAS (USA)
Base Pair offers catalog aptamers to a diverse range of target molecules, including proteins, antibodies, small molecules, toxins, bacterial proteins, cytokines, and more. Aptamers can be purchased with a wide range of modifications for immobilization, conjugation, or direct detection. Choose from the standard modifications listed in our on-line catalog or request a custom ...
by:Champions Oncology, Inc. based inHackensack, NEW JERSEY (USA)
Champions Oncology’s Analytical Testing platforms can be used to gather additional data at the endpoint of a preclinical model or ex vivo assay. Using multiplex cytokine assays with flow cytometry readouts, immune cell cytokine intracellular and extracellular staining upon activation can be assessed. Champions Oncology can also collect ...
Manufactured by:AventaCell BioMedical Corp based inAtlanta, GEORGIA (US) (USA)
Human platelet lysate (hPL) contains abundant growth factors and cytokines necessary for cell growth and is well recognized as an efficient xenogenic-free alternative to FBS for manufacturing cells and cellular ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Protein drugs in a broad sense include all products whose chemical nature is protein or polypeptide, such as hormones, growth factors/cytokines, plasma proteins, enzymes, coagulation factors, antibodies, protein vaccines, ...
Manufactured by:Creative Peptides based inNew York, NEW YORK (USA)
Assistance with experimental set-up and analysis is available for applications such as ELISPOT, cell culture, intracellular cytokine staining and flow cytometry. The CreativePepTM Peptide Library technology can be used for a number of different types of library: > Overlapping peptide library > Alanine Scanning Library > Truncation Library > Random Library > ...
Manufactured by:ACROBiosystems based inNewark, DELAWARE (USA)
Meso Scale Discovery Electrochemiluminescence (MSD) uses sandwich ELISA method coupled with electrochemiluminescence (ECL) detection and plate array technology to provide highly sensitive and multiplexed detection of analytes in a complex biological matrix. MSD can be used for analyzing biomarkers especially most kinds of cytokines and chemokines, perform PK/PD analysis, and ...
Manufactured by:Beta Lifescience based inPaoli, NEW JERSEY (USA)
Beta Lifesciences has accumulated an extensive experience in the development of recombinant proteins. We have rich experience in the expression of recombinant proteins (antibodies, enzymes, membrane proteins, cytokines, etc.) in any species. We provide recombinant protein expression and purification services from small-scale to large-scale. According to the customer's needs, our ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
As the main component of the immune system, T cells protect the body from infections and tumors by a diversity of bio-functions, including recognition and presentation specific antigens, directly killing target cells, secretion cytokines, assisting or inhibiting antibody production by B cells, etc. These functional T cells are distinguished by a variety of surface receptors, ...
Manufactured by:Pluristem Therapeutics Inc. based inHaifa, ISRAEL
Studies have shown that Acute Respiratory Distress Syndrome (ARDS) following viral pneumonia is one of the most common causes of death from COVID-19[1],[2],[3],[4],[5]. A cytokine storm (CS) refers to excessive and uncontrolled release of pro-inflammatory cytokines that commonly present as systemic inflammation, multiple organ failure, and high inflammatory ...