Refine by
High Resolution Spectrometer Services
15 services found
Manufactured by:Pacific Rim Laboratories Inc. (PRL) based inSurrey, BRITISH COLUMBIA (CANADA)
For over 20 years PRL has been analyzing for polychlorinated biphenyls (PCB) using high resolution mass spectrometers (HRMS). We are able to detect PCBs at ultratrace levels in a range of product types including water, sediment, food, pharmaceuticals, and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs offers highly sensitive and accurate Antibody-Drug Conjugate (ADC) Analysis service based on high-throughput liquid chromatography and high-resolution mass spectrometer ...
Manufactured by:Pacific Rim Laboratories Inc. (PRL) based inSurrey, BRITISH COLUMBIA (CANADA)
For over 20 years PRL has been analyzing for polychlorinated dibenzodioxins (PCDD) and polychlorinated dibenzofurans (PCDF). Using high resolution mass spectrometers (HRMS) we are able to detect dioxins and furans at ultratrace levels in a range of product types including water, soil, food, pharmaceuticals and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Glycosylation is an important post-translational modification of proteins. Based on the different linkage modes between the glycan and peptide chains, protein glycosylation can be divided into N-glycosylation and O-glycosylation. N-glycosylation involves the linkage between the reducing end of N-acetylglucosamine (GlcNAc) and the nitrogen atoms on certain asparagine (Asn) side chain amides in the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Oligonucleotide sequence analysis is a biotechnological method for identifying the types and sequences of nucleotides in short DNA or RNA fragments (typically 20-30 nucleotides). This technique plays a critical role across numerous biological and medical disciplines. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Unknown protein identification refers to the process of identifying, studying, and annotating proteins that are not fully understood in terms of function and structure. This process mainly includes protein molecular weight determination, amino acid sequence determination, structure prediction, functional analysis, and interaction network analysis. Mass spectrometry technology is an important ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
4D-DIA quantitative proteomics is an emerging high-throughput mass spectrometry technology that combines data-independent acquisition (DIA) strategies with four-dimensional (4D) separation techniques. It involves digesting protein into peptide by protease and separating peptide by liquid chromatography (LC), followed by mass spectrometry (MS) for detection and identification. It enables ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
HPLC peptide mapping analysis integrates the separation capabilities of high-performance liquid chromatography (HPLC) with the qualitative and quantitative capabilities of mass spectrometry (MS). Utilizing the LC-MS/MS platform, which combines HPLC with tandem high-resolution mass spectrometry, peptides are effectively separated by HPLC and their mass and charge are measured by MS. This allows ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Native mass spectrometry (Native MS) facilitates direct determination of a protein's molecular weight. It facilitates the study of intact proteins, non-covalent protein-protein interactions, and protein-ligand complexes within biological systems, addressing the limitations of traditional mass spectrometry technologies in the precise quantification of complex drug ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Peptides are compounds formed by multiple amino acids linked by peptide bonds and can be prepared via recombinant DNA expression, biological extraction, or chemical synthesis. Peptides represent a unique class of drugs with certain characteristics of small molecule drugs as well as properties of large proteins and other biologics. Most intrinsic signaling molecules are peptide-based, such as ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Biopharmaceutical stability analysis is crucial for assessing the safety, efficacy, and quality of biopharmaceuticals throughout their storage, transportation, and usage. This analysis evaluates changes in the chemical, physical, microbiological, and biological properties of the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Ubiquitin (Ub), a small molecule protein composed of 76 amino acids with a molecular weight of approximately 8.5 kDa, is highly conserved throughout evolution. It contains seven lysine (Lys) sites (K6, K11, K27, K29, K33, K48, and K63), one methionine (Met) site at the N-terminus (M1), and one glycine (Gly) site at the C-terminus (G76). Ubiquitin molecules form ubiquitin chains through these ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Protein mutation refers to the alteration in the amino acid composition or sequence of a protein, which subsequently leads to changes in the structure and function of the protein. Protein mutations can occur naturally or be induced artificially. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Hydrogen deuterium exchange mass spectrometry (HDX MS) represents a sophisticated technique in mass spectrometry for investigating the spatial conformation of proteins, extensively employed across academia and the biopharmaceutical industry for the analysis of protein structures. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
With the rapid development of biotechnology, drug research and development has gradually entered a new era of precision and personalization. Targeted Protein Degradation (TPD) drugs are an emerging therapeutic strategy that utilizes the body's ubiquitin-proteasome system to degrade specific pathological proteins to achieve precise treatment. As an important new class of therapeutic drugs, TPD ...