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Surface Plasmon Resonance Services
19 services found
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Custom surface plasmon resonance (SPR) technology services for drug discovery. ...
Manufactured by:Creative Peptides based inNew York, NEW YORK (USA)
Surface Plasmon Resonance imaging (SPRi), namely surface plasmon resonance microscopy (SPRM), is a real-time, label-free, and high-throughput technique which is used to study biomolecular interactions based on detecting the refractive index changes resulting from molecular binding. ...
Manufactured by:Creative Biolabs based inShirley, NEW YORK (USA)
Scientists from Creative Biolabs are competent for performing antibody affinity and kinetics measurement with the most advanced Biacore, ProteOn, Octet systems, etc. These systems are mainly based on the optical phenomena technologies - surface plasmon resonance (SPR) and bio-layer interference (BLI), which enable a direct detection and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Developed in the 1990s, Surface plasmon resonance technology (SPR) offers an innovative methodology for detecting interactions between ligands and analytes on biosensor chips, grounded in SPR principles. ...
Manufactured by:Aviva Systems Biology Corporation based inSan Diego, CALIFORNIA (USA)
However, antibodies as drugs or diagnostic agents present significant analytical challenges because antibodies are large, complex, and heterogeneous molecules. Surface Plasmon Resonance (SPR) is a powerful analytical technology that is well suited for analyzing and characterizing antibodies. SPR can be used to measure the antibody-antigen binding ...
by:AFFINImeter by Software 4 Science Developments based inSantiago de Compostela, SPAIN
Our services and our proprietary software allow us to support decision making in hit validation and lead optimization of drug candidates by Isothermal Titration Calorimetry. ...
Manufactured by:JPK BioAFM Business - Bruker Nano GmbH based inBerlin, GERMANY
From inquiry to installation, and throughout the lifetime of the instrument, Bruker services provide our customers with dedicated and personalized support to ensure their instruments maintain maximized uptime and optimized ...
by:LifeSensors Inc based inMalvern, DELAWARE (USA)
LifeSensors understands that early drug discovery programs are both labor intensive and time consuming. Besides involvement of both cellular and biochemical assays, biophysical characterization of potential hits is also a vital part of the drug discovery process – from early hit finding to mechanistic profiling during lead optimization. As part of our ongoing efforts to provide customers ...
Manufactured by:Rentschler Biopharma SE based inLaupheim, GERMANY
Our drug substance manufacturing in state-of-the-art cGMP facilities meets the highest standards of the biopharmaceutical industry. To guarantee this, we follow high-quality standards within our internal processes and our team. Comprehensive quality management and precise, as well as reliable quality control, ensure excellent performance and results. We pay attention to the continuous monitoring ...
by:Base Pair Biotechnologies, Inc. based inPearland, TEXAS (USA)
Aptamer discovery is a complex process. Customized libraries and selection techniques are employed to achieve selective binding to a target of interest under anticipated conditions. In some cases, selected aptamers may not quite achieve the degree of affinity or stability required for a specific end-use application. In addition, aptamer modification for immobilization or signal generation is ...
Manufactured by:Exscientia based inOxford, UNITED KINGDOM
Only with continual feedback between experiment and prediction can machine learning models be refined and deliver against complex therapeutic ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The protein corona of nanoparticles exhibits several advantageous properties. Firstly, it can selectively enrich or deplete specific proteins within the corona, independently of the protein composition present in biological fluids. This capability is particularly beneficial for protein identification and characterization, especially within the realm of plasma proteomics. Secondly, the composition ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The inauguration of monoclonal antibodies (mAbs), derived from mice, were immunogenic in humans. These molecules were first synthesized in 1975 by Georges Köhler and César Milstein through the use of hybridoma technology. Later, in 1984, another milestone was achieved with the production of chimeric human antibodies via recombinant DNA technology. Hybridoma technology facilitates the creation of ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Recombinant protein drugs are produced using recombinant DNA or RNA technologies. This involves the integration of target protein genes into recombinant vectors, which are then introduced into host cells to synthesize specific recombinant proteins. These drugs are primarily designed to replace or supplement proteins that are deficient due to genetic disorders or diseases. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Drug screening refers to the evaluated process of substances (samples) potentially used as drugs, assessing their biological activity, pharmacological effects, and therapeutic value through appropriate methods. This process encompasses biochemical and cellular levels of screening, divided into high-throughput screening (HTS) and virtual ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Receptors are biomolecules that can bind with hormones, neurotransmitters, drugs, or intracellular signaling molecules and are capable of inducing changes in cellular function. Receptors are categorized based on their cellular location into cell surface receptors and intracellular receptors. Each receptor typically has two active sites: one that recognizes and binds to the ligand and another ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Due to their large surface area-to-volume ratio, nanoparticles (NPs) rapidly adsorb proteins on their surface upon contact with biological fluids, forming a "protein corona (PC)." The binding between NPs and proteins is primarily mediated by intermolecular forces such as hydrogen bonding, hydrophobic interactions, electrostatic interactions, and van der Waals forces. During this process, proteins ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Structural biology has always played a vital role in drug discovery because it provides the most direct and visible atomic-level information on drug targets and can be applied to every step of preclinical drug development, including target identification and design as well as lead compound optimization. Based on atomic resolution information about the active or regulatory sites of target ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Small molecule drugs, predominantly chemically synthesized drugs with molecular weight lower than 1000 Da. These drugs are characterized by their widespread use and mature theoretical foundations. Statistically, small molecule drugs comprise about 98% of commonly used medications. ...