MtoZ Biolabs - Model proteomics-analysis-strategies -Proteomics Analysis Strategy

Proteomics analysis includes analyzing the structure and function of proteins, post-translational modifications (PTMs), protein localization, protein expression, and the interactions among proteins, etc. Based on different analytical content, different proteomics analysis techniques and strategies can be adopted.

Mass spectrometry (MS) is one of the most commonly used techniques in proteomics analysis. Currently, proteomics analysis strategies based on MS mainly include bottom-up proteomics and top-down proteomics. In bottom-up proteomics, proteins need to be digested into peptides before mass spectrometric analysis, and this strategy is adopted by common label-free and labeling quantitative proteomics techniques. In top-down proteomics, protein are not digested but are directly analyzed, which can preserve most of the features of proteins with unstable structures that are mostly destroyed in the bottom-up strategy, and also reduces the time consumption of digestion. Researchers can choose the appropriate strategy for proteomics analysis according to different research needs.

MtoZ Biolabs provides various proteomics analysis services using the Thermo Fisher Orbitrap Fusion Lumos mass spectrometry platform combined with nanoLC-MS/MS nanoscale chromatography.

1. Top-down Proteomics

2. DIA-PRM Proteomics

3. PCT-DIA Proteomics

MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.

MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.

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