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Liquid Chromatography System Services
409 services found
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs operates a leading-edge platform for peptide synthesis, equipped with several automated multi-channel peptide synthesizers, high-performance liquid chromatography (HPLC) systems, and mass spectrometers. This setup ensures the delivery of high-quality peptide products with rapid turnaround and competitive pricing. ...
Manufactured by:Indoor Biotechnologies, Inc. based inCharlottesville, VIRGINIA (USA)
Indoor Biotechnologies uses a Thermo Fisher Orbitrap platform combined with a Vanquish Flex UHPLC liquid chromatography system. The Q Exactive is a hybrid quadrupole-Orbitrap mass spectrometer, combining a high-performance quadrupole mass filter system with a high resolution, sensitive Orbitrap mass analyzer. The instrument is ...
Manufactured by:Zaiput Flow Technologies based inWaltham, MASSACHUSETTS (USA)
Zaiput specializes in optimizing liquid-liquid extraction processes by selecting the right solvents and refining the extraction and separation conditions for various applications. Utilizing automated equipment and protocols, Zaiput identifies the optimal composition of the extraction phase tailored to specific client requirements. The company's comprehensive service includes the development of ...
Manufactured by:EirGenix, Inc based inNew Taipei City, TAIWAN
Our downstream development team provides a comprehensive development platform for our clients.With this platform, we streamline transfer to deliver successful results for both existing and novel process development and optimization.Previous mammalian project experience includes recombinant protein, fusion protein, and monoclonal antibody. Previous microbial project experience includes ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
During the comparative analysis of metabolites between two sample groups, commonly employed univariate methods include Fold Change Analysis (FC Analysis), the T-test, and the Volcano Plot, which synthesizes the preceding two methodologies. This analysis visually elucidates the significance of metabolite variations between samples, aiding in the identification of potential biomarkers (typically ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Glycerophospholipids are phospholipids based on glycerol, serving as the main components of biological membranes. The diversity of head groups, complex acyl chain combinations, and a broad range of ionization efficiencies pose significant challenges for the accurate quantification of glycerophospholipids. These compounds encompass hundreds of analytes commonly encountered in routine analysis and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Charge heterogeneity is a key attribute of biomolecules such as antibody, enzyme, and protein, affecting the molecule's stability, solubility, and biological activity. Changes of deamidation, oxidation, glycosylation, glycation, the N- or C-terminal, loss of three-dimensional structure, or reduction of disulfide bonds may lead to changes in charge heterogeneity. Since charge heterogeneity ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The primary structure of proteins is fundamental to the biological function of proteins, and determining the primary structure aids in studying the function of proteins. MtoZ Biolabs provides protein primary structure detection service based on mass ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Sphingosine (SPH) is a long-chain aliphatic compound with an acyclic carbon skeleton, typically featuring a 2-amino-1,3-diol functional group. The primary SPH in mammalian tissues are sphingosine (2S,3R-d-erythro-2-amino-1,3-octadec-4E-ene-diol), sphinganine (2S,3R-d-erythro-2-amino-1,3-octadecane diol), and 4-hydroxy-sphinganine (2S,3S,4R-erythro-2-amino-1,3,4-octadecanetriol). In yeast, the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The COG (Clusters of Orthologous Groups) database is an early and widely used resource for the homologous classification of gene products, based on extensive comparisons of protein sequences from various ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Data completeness and accuracy is crucial for subsequent statistical and biological results. After verifying the experimental design and the accuracy of the collected data, MtoZ Biolabs conducts an initial integrity check. This involves removing or imputing missing values, excluding outliers, and normalizing data across samples and metabolites to allow for parallel comparisons. Metabolites with ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
In contrast to principal component analysis (PCA), both partial least squares discrimination analysis (PLS-DA) and orthogonal PLS-DA (OPLS-DA) are supervised statistical methods for discriminative analysis. These methods develop models that correlate metabolite expression levels with sample categories to facilitate prediction of the category of ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To validate the selection of differentially expressed proteins or characteristic differentially expressed proteins, cluster analysis can be performed to group proteins based on expression trends, facilitating more intuitive proteomic data analysis. Services at MtoZ Biolabs 1. Hierarchical Cluster Analysis 2. K-means Cluster ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
In top-down proteomics analysis, intact protein molecular ions generated by ESI or MALDI are introduced into a mass analyzer and undergo gas-phase fragmentation. Top-down analysis facilitates the direct observation of C-terminal and N-terminal truncations and the differentiation of isomers through different ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs offers targeted organic acids analysis service using GC/MS, with high accuracy, specificity, and sensitivity. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
MtoZ Biolabs offers targeted aldehydes analysis service using UPLC/TripleQuad5500, with high accuracy, specificity, and ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
The extinction coefficient is a unit of measurement that determines the absorption intensity of a chemical substance at a specific wavelength. The molar extinction coefficient of proteins at 280 nm is almost entirely dependent on the number of aromatic residues, especially tryptophan, and can be predicted from the amino acid sequence. If the molar extinction coefficient is known, it can be used ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Molecular weight is a basic physicochemical parameter of organic compounds, generally referring to the relative molecular mass, which is the sum of the relative atomic masses of each atom in the compound's chemical formula. The correctness of the molecular weight often represents whether the structure of the measured organic compound or biomacromolecule is ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Glycosidic bonds rarely affect the function of glycoproteins, thus they are usually not necessary to determine. However, the glycan structure of glycoproteins is highly complex, and assessing the configuration and location of N-glycan glycosidic bonds is helpful for analyzing the structure of glycoproteins. There are five common types of N-glycosidic bonds, with the most common being the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Principal Component Analysis (Principal Component Analysis, PCA) is the linear recombination of all metabolites originally identified, forming a set of new comprehensive variables, and selecting 2-3 comprehensive variables from them based on the analyzed problem, to reflect as much information of the original variables as possible, thus achieving the purpose of dimension reduction. At the same ...