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Hplc Articles & Analysis

344 articles found

How CROs and Biotech Firms Use Pomalidomide Derivatives for Rapid PROTAC Screening

How CROs and Biotech Firms Use Pomalidomide Derivatives for Rapid PROTAC Screening

Each product is supplied with full analytical characterization (HPLC, LC-MS, NMR) to ensure consistency across parallel assays and multi-target screening programs. ...

ByBOC Sciences


From Drought to Salt Stress: What Proline Levels Reveal About Plant Health

From Drought to Salt Stress: What Proline Levels Reveal About Plant Health

Alternatives and Modern Approaches Although the ninhydrin method is widely used, other techniques can provide greater accuracy or sensitivity: l High-Performance Liquid Chromatography (HPLC): Separates and quantifies free amino acids with excellent precision. ...

ByLifeasible


Can Herbal Medicine Protect Against Microplastic-Induced Lung Damage?

Can Herbal Medicine Protect Against Microplastic-Induced Lung Damage?

Polystyrene microplastics (PSMPs), small plastic fragments measuring less than 5 µm in diameter, are increasingly recognized as harmful air-borne pollutants. Studies demonstrate their ability to penetrate deep into the lungs, where they can induce oxidative stress, inflammation and airway remodeling. A recent study by Balkrishna et al. (2025) investigates these effects in a murine model and ...

BySCIREQ - an emka TECHNOLOGIES Company


Phytochemical Tests: Common Questions and Key Precautions

Phytochemical Tests: Common Questions and Key Precautions

Accurate quantification requires advanced techniques such as HPLC, LC-MS, or GC-MS. 4. Why do protocols vary between publications? ...

ByLifeasible


Fluorescent Biopolymers: Key Insights and Common Questions Answered

Fluorescent Biopolymers: Key Insights and Common Questions Answered

A 5°C temperature increase above the optimal 25°C during peptide polymer synthesis reduced purity from 95% to 80% (measured by HPLC).​ l Purification: Separating products from unreacted materials is difficult. ...

ByMatexcel


Comprehensive Insights into Tryptamine Analysis and Its Biological Significance

Comprehensive Insights into Tryptamine Analysis and Its Biological Significance

Chromatographic Techniques High-resolution separation methods such as High-Performance Liquid Chromatography (HPLC), Ultra-Performance Liquid Chromatography (UPLC), and Gas Chromatography (GC) are standard techniques for tryptamine analysis. ...

ByCreative Proteomics


Safeguarding product quality in drug manufacturing with NIR spectroscopy

Safeguarding product quality in drug manufacturing with NIR spectroscopy

The pharmaceutical industry is under constant pressure to ensure product integrity, regulatory compliance, and efficiency in manufacturing. As production processes become more complex, the need for real-time, data-driven quality control has never been greater. Near-infrared (NIR) spectroscopy is essential for advanced monitoring of drug manufacturing, enabling rapid, non-destructive analysis ...

ByGalaxy Scientific Inc


Why use NIR for pharmaceutical quality control?

Why use NIR for pharmaceutical quality control?

Pharmaceutical manufacturers face growing challenges in ensuring product quality, maintaining regulatory compliance, and safeguarding against counterfeit drugs. Near-infrared (NIR) spectroscopy is an important tool in this arena, offering rapid, non-destructive analysis for raw material identification, impurity detection, and counterfeit screening. By integrating NIR spectroscopy into quality ...

ByGalaxy Scientific Inc


Advancing Cancer Treatment: The Role of Radioactive Drug Conjugate Development Services and Pre-Clinical Analysis Services for RDCs

Advancing Cancer Treatment: The Role of Radioactive Drug Conjugate Development Services and Pre-Clinical Analysis Services for RDCs

High-performance liquid chromatography(HPLC) and mass spectrometry (MS) are commonly employed techniques in this analysis. ...

ByAlfa Cytology


ADC Development and Production: Innovations and Best Practices

ADC Development and Production: Innovations and Best Practices

Techniques such as mass spectrometry, analytical HPLC, and functional assays are employed to assess the structure, efficacy, and safety of the ADC. ...

ByCreative Biogene


Enhancing Wellness with Vitamins Quantitative Analysis

Enhancing Wellness with Vitamins Quantitative Analysis

Here are some common methods: High-Performance Liquid Chromatography (HPLC): HPLC is one of the most widely used methods for vitamin analysis. ...

ByCreative Proteomics


Decoding Plant Hormone Signals for Agriculture and Biotechnology   

Decoding Plant Hormone Signals for Agriculture and Biotechnology  

Techniques for Plant Hormone Analysis Advanced analytical techniques are employed to measure and analyze plant hormones: Chromatographic Techniques: High-performance liquid chromatography (HPLC) and gas chromatography (GC) are widely used to separate and quantify hormones due to their specificity and sensitivity. HPLC, often coupled with mass spectrometry (MS), ...

ByCreative Proteomics


GMP Cell Bank Characterization: Ensuring Quality and Safety in Biopharmaceuticals

GMP Cell Bank Characterization: Ensuring Quality and Safety in Biopharmaceuticals

Analytical Chemistry: Methods like HPLC (High-Performance Liquid Chromatography) and mass spectrometry can be used to analyze secreted products, confirming the functional characteristics of the cells. ...

ByCreative Bioarray


Exosome Lipidomics and Metabolomics: A New Frontier in Disease Diagnosis and Therapy

Exosome Lipidomics and Metabolomics: A New Frontier in Disease Diagnosis and Therapy

In addition, gas chromatography (GC) and high-performance liquid chromatography (HPLC) are employed to analyze volatile metabolites and lipids with distinct physicochemical properties. ...

ByCreative Biostructure


Comprehensive Guide to Glucosinolates: Plant Defense, Human Health, and Cutting-Edge Analytical Methods   

Comprehensive Guide to Glucosinolates: Plant Defense, Human Health, and Cutting-Edge Analytical Methods  

High-Performance Liquid Chromatography (HPLC): HPLC is another reliable method for separating and quantifying glucosinolates, especially when coupled with UV or fluorescence detection. ...

ByCreative Proteomics


Unveiling the Role of Nicotinamide Adenine Dinucleotide (NAD): A Key Player in Cellular Metabolism and Disease Research   

Unveiling the Role of Nicotinamide Adenine Dinucleotide (NAD): A Key Player in Cellular Metabolism and Disease Research  

Common approaches include: High-Performance Liquid Chromatography (HPLC): This is a reliable and widely used method for separating and quantifying NAD and NADH in complex biological samples. ...

ByCreative Proteomics


Amino Acid Determination: Precise Content Analysis

Amino Acid Determination: Precise Content Analysis

High-Performance Liquid Chromatography (HPLC)(1) PrincipleHPLC can separate, identify, and quantify various components in complex samples. ...

ByMtoZ Biolabs


Exploring Plant Pigment Detection: Methods, Applications, and Advances

Exploring Plant Pigment Detection: Methods, Applications, and Advances

High-Performance Liquid Chromatography (HPLC) HPLC is a highly precise method for separating and quantifying individual pigments. ...

ByLifeasible


Comparison Table of Certified Reference Materials (CRMs) and Reference Materials (RMs)

Comparison Table of Certified Reference Materials (CRMs) and Reference Materials (RMs)

This case highlights the indispensable role of CRMs in high-stakes regulatory environments where precision and documentation are paramount.Case Study 2: RMs in Pharmaceutical Method DevelopmentOne pharmaceutical company is in the process of establishing a new High Performance Liquid Chromatography (HPLC) process for testing active pharmaceutical ingredients (APIs) in a drug ...

ByAlfa Chemistry


Analysis of Components of Antibody Drug Culture Medium

Analysis of Components of Antibody Drug Culture Medium

High-Performance Liquid Chromatography (HPLC)(1) HPLC can be used to quantitatively analyze various components in the medium, such as amino acids, sugars, vitamins, and other small molecules.(2) This technique provides high resolution and can separate and quantify individual components in complex mixtures.2. ...

ByMtoZ Biolabs

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