MtoZ Biolabs - Model acyl-coas -Acetyl CoA Analysis Service

Acetyl-CoA, an activated form of acetate, is formed by an acetyl group (CH3CO-) bonding to the thiol group of coenzyme A via a high-energy thioester bond. It is product of the decarboxylation of pyruvate produced by β-oxidation and glycolysis of fatty acid (FA). In the initial step of the tricarboxylic acid cycle (TAC), the acetyl group is transferred to oxaloacetate to form citrate, and this cycle is also called the "citric acid cycle". MtoZ Biolabs utilizes ACQUITY UPLC/TripleQuad5500 (Waters/AB Sciex) for the quantitative and qualitative analysis of acetyl-CoA and its related substances.

Serum, plasma, urine, bile, bile acids; cell, animal tissues including liver, brain, and feces; plants, yeast, microorganisms, etc.

1. Sample requirements

(1) Blood, bile, etc.: 10 µL

(2) Various tissues: 10 mg

(3) Feces, etc.: 10 mg

For other sample types and sizes, please contact MtoZ Biolabs salesman.

2. Sample Transportation

Considering the evaporation rate of 3-4 kg of dry ice per day, ensure ample dry ice used for mailing (preferably larger dry ice pieces as they evaporate slower), and sealed in foam boxes. Opt for the fastest possible mailing method to reduce sample degradation during transport.

1. Experimental Procedures

2. Relevant Mass Spectrometry Parameters

3. Quantitative or Qualitative Information of Identified Substances

4. Mass Spectrometry Images

5. Raw Data

MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.

MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.

Email: [email protected]