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Oncogene Services
13 services found
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
SW480 cells express elevated levels of p53 protein. The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb, sis and fos oncogenes. N-myc oncogene expression was not detected. Matrilysin, a metalloproteinase associated with tumor invasiveness, is not expressed. SW480 cells have been reported to produce GM-CSF. The GFP Stable Cell Line-SW480 ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
HSP90 plays a crucial role in stabilizing denatured proteins that have become misfolded or unfolded because of cellular stress and by aiding in their re-folding. So far, many of the proteins identified as HSP90 clients are key components of the oncogenic phenotype involved in controlling many of the hallmarks of cancer. ...
Manufactured by:Alfa Chemistry based inNew York, NEW YORK (USA)
MRTX0902 is a potent SOS1 inhibitor which can be used for the therapeutic intervention of KRAS-driven (Kirsten rat sarcoma virus driven) cancers. Rat sarcoma (RAS) is the most frequently mutated oncogene in human cancer, with KRAS being the most commonly mutated RAS isoform. Overall, KRAS accounts for 85% of RAS mutations observed in human cancers and is present in 35% of lung ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
According to current regulations (ICH guideline Q5A), we must consider the following aspects, including the origin and history of the cell line cellular morphology and growth characteristics, cellular identity, purity of the cell lines, tumorigenicity, and oncogenicity, genetic stability, etc. At Creative Bioarray, cell line characterization is performed for master cell banks ...
Manufactured by:ImCare Biotech, LLC based inDoylestown, PENNSYLVANIA (USA)
In addition, high levels of SPIK are closely associated with early recurrence in cancer patients following surgical resection. Because recurrence of cancer often implies the immune system’s inability to clear lingering oncogenic cells, early cancer recurrence in patients with high levels of SPIK suggests that the overexpression of SPIK may interfere with the elimination of ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Compared with normal cells, tumor cells have undergone a series of genetic and epigenetic alterations that, in general, underlie cancer development, progression, and drug resistance. Tumor-derived cell lines have served as important models to advance our understanding of oncogene function and therapeutic responses. Creative Bioarray provides human tumor cells sourced from a ...
by:Strand Life Sciences Pvt. Ltd. based inBangalore, INDIA
Laboratories running NGS-based clinical tests are challenged with the labor of variant interpretation. To support our clinical diagnostics business, we have built up databases of curated variants across 3 different application areas: ...
Manufactured by:Yashraj Biotechnology Ltd based inNavi Mumbai, INDIA
Yashraj Biotechnology Ltd.’s (YBL) offers Development of Primary Cell line(s), both from normal and tumor tissues. YBL offers Transformation of cell lines by introduction of external DNA that drives the Transformation process by sustaining proliferative signaling, evading growth suppressors, resisting cell death, enabling replicative immortality, inducing angiogenesis, and activating ...
Manufactured by:Biomatik Corporation based inKitchener, ONTARIO (CANADA)
Biomatik has been proudly serving 10,000+ scientists since 2002. If you cannot find a protein from our extensive protein catalog to suit your research needs, then our custom protein production service team can help. Our custom protein production service utilizes our proprietary codon optimization algorithm and in-house gene synthesis technology to offer customers the best customized research ...
Manufactured by:Ulisse BioMed based inUdine, ITALY
Ulisse BioMed proposes a specific offer for the detection and genotyping of Human Papillomavirus (HPV) to physicians and professionals in the gynecological ...
Manufactured by:Lupin Limited based inMumbai, INDIA
The NDDD team has developed a pipeline of highly differentiated and innovative new chemical entities in focused therapeutic areas of Oncology, Immunology and Metabolic ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Protein phosphorylation is a common post-translational modification in eukaryotes. Eukaryotic cell protein phosphorylation is divided into two types: serine (Ser)/threonine (Thr) phosphorylation and tyrosine (Tyr) phosphorylation. Although the proportion of Tyr phosphorylation is small, it plays an extremely important role in the fate of cells and individuals, and is closely related to diseases ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Residual DNA (rDNA) refers to the aggregate of deoxyribonucleic acid (DNA) and fragments extracted from recombinant host cells, commonly termed as residual host cell DNA. The cell substrates employed in producing biologics like vaccines encompass primary cells, continuously passaged cell lines, and human diploid ...