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MtoZ BiolabsModel lipidomics-maldi-imaging -Lipidomics MALDI Imaging

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MALDI-IMS is a powerful tool for examining the distribution of lipids in tissues. As an ion source, MALDI is particularly well-suited for thin tissue sections and is extensively employed for analysis of tissue samples. The benefits of MALDI-IMS include: 1) Simplified extraction steps; 2) Reduced sample loss; 3) Omission of complex deduction processes; 4) Provision of detailed spatial organization and distribution data.
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MALDI-IMS is a powerful tool for examining the distribution of lipids in tissues. As an ion source, MALDI is particularly well-suited for thin tissue sections and is extensively employed for analysis of tissue samples. The benefits of MALDI-IMS include: 1) Simplified extraction steps; 2) Reduced sample loss; 3) Omission of complex deduction processes; 4) Provision of detailed spatial organization and distribution data.

MALDI enables the imaging of a vast array of endogenous lipids. For most of endogenous lipids, mass spectrometry imaging remains the sole method for analyzing their spatial distribution. The critical role of lipidomics in exploring developmental or pathological processes in tissue sections makes MALDI imaging an invaluable tool for biomarker discovery.

Nahon, J. E. et al. Atherosclerosis. 2019.

MtoZ Biolabs provides rapid, reliable, and cost-effective lipidomics MALDI imaging services capable of detecting thousands of lipids. The results yield histological maps of lipid biomolecules, pinpointed and characterized by their mass-to-charge ratios (m/z). Imaging data can be normalized to total ion current to quantify lipid abundance, and are also suitable for statistical analysis.


MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.

MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.

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