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Mitochondrial Dysfunction Equipment & Supplies

112 equipment items found

MedChemExpress - Model Tebufenpyrad - 119168-77-3

MedChemExpress - Model Tebufenpyrad - 119168-77-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tebufenpyrad can induce mitochondrial dysfunction and oxidative damage. Tebufenpyrad induces dose-dependent cell death on N27 cells, with an EC50 value of 3.98 ...
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MedChemExpress - Model Tebufenpyrad - 119168-77-3

MedChemExpress - Model Tebufenpyrad - 119168-77-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tebufenpyrad can induce mitochondrial dysfunction and oxidative damage. Tebufenpyrad induces dose-dependent cell death on N27 cells, with an EC50 value of 3.98 ...
CONTACT SUPPLIER

ViCardia - Model GP531 - Potent, Long-Lasting, Infusion Therapy

ViCardia - Model GP531 - Potent, Long-Lasting, Infusion Therapy

Manufactured by:ViCardia Therapeutics, Inc.   based inSan Francisco, CALIFORNIA (USA)
ViCardia is entering Phase 2 with GP531, a potent, long-lasting, infusion therapy that treats mitochondrial dysfunction that leads to chronic heart failure and ultimately to acute decompensated heart failure. ...
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MedChemExpress - Model Nerol - 106-25-2

MedChemExpress - Model Nerol - 106-25-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal ...
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MedChemExpress - Model Tebufenpyrad (Standard) - 119168-77-3

MedChemExpress - Model Tebufenpyrad (Standard) - 119168-77-3

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Tebufenpyrad (Standard) is the analytical standard of Tebufenpyrad. This product is intended for research and analytical applications. Tebufenpyrad can induce mitochondrial dysfunction and oxidative damage. Tebufenpyrad induces dose-dependent cell death on N27 cells, with an EC50 value of 3.98 ...
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MedChemExpress - Model VLX600 - 327031-55-0

MedChemExpress - Model VLX600 - 327031-55-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
VLX600 is an iron-chelating inhibitor of oxidative phosphorylation (OXPHOS). VLX600 causes mitochondrial dysfunction and induces a strong shift to glycolysis. VLX600 displays selective cytotoxic activity against malignant cell and induces autophagy. Anticancer ...
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MedChemExpress - Model USP30 inhibitor 11 - 2067332-64-1

MedChemExpress - Model USP30 inhibitor 11 - 2067332-64-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
USP30 inhibitor 11 is a selective and potent ubiquitin specific peptidase 30 (USP30) inhibitor with an IC50 of 0.01 μΜ, the example 83 extracted from patent WO2017009650A1. USP30 inhibitor 11 is used for the study of cancer and conditions involving mitochondrial ...
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MedChemExpress - Model Pyraclostrobin - 175013-18-0

MedChemExpress - Model Pyraclostrobin - 175013-18-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Pyraclostrobin is a highly effective and broad-spectrum strobilurin fungicide. Pyraclostrobin can induce oxidative DNA damage, mitochondrial dysfunction and autophagy through the activation of AMPK/mTOR signaling. Pyraclostrobin can be used to control crop ...
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MedChemExpress - Model 2-Thenoyltrifluoroacetone - 326-91-0

MedChemExpress - Model 2-Thenoyltrifluoroacetone - 326-91-0

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
2-Theoyltrifluoroacetone is a chelating agent and mitochondrial electron transfer chain inhibitor, with a IC50 value of 51.5 μM. 2-Thermoyltrifluoroacetone can chelate with various metal ions and has cytotoxicity and anti-tumor activity, which is expected to play an important role in the treatment of mitochondrial dysfunction related ...
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MedChemExpress - Model Isolongifolene - 1135-66-6

MedChemExpress - Model Isolongifolene - 1135-66-6

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Isolongifolene ((-)-Isolongifolene) is a tricyclic sesquiterpene isolated from Murraya koenigii. Isolongifolene attenuates Rotenone-induced oxidative stress, mitochondrial dysfunction and apoptosis through the regulation of PI3K/AKT/GSK-3β signaling pathways. Isolongifolene has antioxidant, anti-inflammatory, anticancer and neuroprotective ...
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MedChemExpress - Model Pendimethalin - 40487-42-1

MedChemExpress - Model Pendimethalin - 40487-42-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Pendimethalin is an orally active herbicide that controls annual grasses and certain broadleaf weeds. Pendimethalin induces Apoptotic cell death through activating ER stress-mediated mitochondrial dysfunction in human umbilical vein endothelial ...
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MedChemExpress - Model (S)-Coriolic acid - 29623-28-7

MedChemExpress - Model (S)-Coriolic acid - 29623-28-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
(S)-Coriolic acid is an important intracellular signal agent and is involved in cell proliferation and differentiation in various biological systems. (S)-Coriolic acid induces mitochondrial dysfunction and airway epithelial ...
CONTACT SUPPLIER

MedChemExpress - Model KL1333 - 1800405-30-4

MedChemExpress - Model KL1333 - 1800405-30-4

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
KL1333 reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. KL1333 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. KL1333 protects against Cisplatin-induced ototoxicity in mouse cochlear ...
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MedChemExpress - Model Ciprofloxacin (Standard) - 85721-33-1

MedChemExpress - Model Ciprofloxacin (Standard) - 85721-33-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
This product is intended for research and analytical applications. Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin ...
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MedChemExpress - Model Ciprofloxacin lactate - 97867-33-9

MedChemExpress - Model Ciprofloxacin lactate - 97867-33-9

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ciprofloxacin (Bay-09867) lactate is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin lactate induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin lactate has anti-proliferative activity and induces apoptosis. Ciprofloxacin lactate is a fluoroquinolone antibiotic, ...
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MedChemExpress - Model Perhexiline - 6621-47-2

MedChemExpress - Model Perhexiline - 6621-47-2

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Perhexiline is an orally active CPT1 and CPT2 inhibitor that reduces fatty acid metabolism. Perhexiline induces mitochondrial dysfunction and apoptosis in hepatic cells. Perhexiline can cross the blood brain barrier (BBB) and shows anti-tumor activity. Perhexiline can be used in the research of cancers, and cardiovascular disease like ...
CONTACT SUPPLIER

MedChemExpress - Model (S)-Coriolic acid - 29623-28-7

MedChemExpress - Model (S)-Coriolic acid - 29623-28-7

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
(S)-Coriolic acid is an important intracellular signal agent and is involved in cell proliferation and differentiation in various biological systems. (S)-Coriolic acid induces mitochondrial dysfunction and airway epithelial ...
CONTACT SUPPLIER

MedChemExpress - Model Ciprofloxacin (monohydrochloride) (Standard) - 93107-08-5

MedChemExpress - Model Ciprofloxacin (monohydrochloride) (Standard) - 93107-08-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin ...
CONTACT SUPPLIER

MedChemExpress - Model Ciprofloxacin - 85721-33-1

MedChemExpress - Model Ciprofloxacin - 85721-33-1

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial ...
CONTACT SUPPLIER

MedChemExpress - Model Ciprofloxacin monohydrochloride - 93107-08-5

MedChemExpress - Model Ciprofloxacin monohydrochloride - 93107-08-5

Manufactured by:MedChemExpress LLC (MCE)   based inMonmouth Junction, NEW JERSEY (USA)
Ciprofloxacin (Bay-09867) monohydrochloride is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin monohydrochloride induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin monohydrochloride has anti-proliferative activity and induces apoptosis. Ciprofloxacin ...
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